Galer B S, Lipton R B, Kaplan R, Kaplan J G, Arezzo J, Portenoy R K
J Pain Symptom Manage. 1991 Feb;6(2):92-7. doi: 10.1016/0885-3924(91)90523-7.
We describe a patient with burning pain in both feet associated with local autonomic disturbances following bilateral traumatic sciatic mononeuropathies. The diagnosis of a sympathetically maintained pain was confirmed through a prompt response to sympathetic blockade. Although a mild alcohol-nutritional neuropathy was found, the clinical findings strongly suggested a diagnosis of bilateral causalgia. Clinical evaluation and quantitative sensory testing were performed prior to and after successive unilateral lumbar sympathetic nerve blocks. After unilateral blockade, bilateral improvement was recorded in measures of pain, sudomotor function, and foot temperature. Other measures of autonomic function showed variable responses to sympathetic blockade. Quantitative sensory testing revealed a dramatic alteration in the contralateral limb's thermal sense following unilateral block. This case underscores the potential for bilateral causalgia and provides additional evidence for a central mechanism operating in this disorder. The relationship between bilateral causalgia and the "burning feet syndrome" in alcoholic neuropathy is discussed.
我们描述了一名患者,双侧创伤性坐骨单神经病后双足出现灼痛并伴有局部自主神经功能障碍。通过对交感神经阻滞的迅速反应,证实了交感神经维持性疼痛的诊断。尽管发现有轻度酒精性营养性神经病变,但临床发现强烈提示双侧灼性神经痛的诊断。在连续进行单侧腰交感神经阻滞后,进行了临床评估和定量感觉测试。单侧阻滞后,疼痛、汗腺运动功能和足部温度测量均记录到双侧改善。自主神经功能的其他测量对交感神经阻滞表现出不同的反应。定量感觉测试显示,单侧阻滞后对侧肢体的热感觉发生了显著改变。该病例强调了双侧灼性神经痛的可能性,并为该疾病中存在的中枢机制提供了额外证据。还讨论了双侧灼性神经痛与酒精性神经病变中“灼足综合征”的关系。