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33例甲型H1N1流感临床分析

[A clinical analysis of 33 cases of H1N1 influenza A].

作者信息

Yan Jie, Wang Yu-guang, Xiao Jiang, Zhang Su-juan, Chen Zhi-hai, Guo Li-min, Wang Yu, Li Xin, Xu Yan-li, Zhang Ming, Li Xing-wang

机构信息

Infectious Disease Diagnosis and Treatment Center, Beijing Ditan Hospital, Beijing 100015, China.

出版信息

Zhonghua Nei Ke Za Zhi. 2009 Oct;48(10):830-2.

Abstract

OBJECTIVE

To review the clinical characteristics of H1N1 influenza A, and suggest the clinical practices for the diagnosis and treatment of H1N1 influenza A in the future.

METHODS

Thirty-three cases of H1N1 influenza A hospitalized in Beijing Ditan Hospital from May 15 to June 22, 2009 were studied and the clinical data were statistically analyzed with SPSS 11.0 for Windows.

RESULTS

Twenty-five of the 33 patients had a history of travelling in America, Canada, Japan etc within a week; the latent period was between 1 and 6 days in 12 close contact patients. The main symptoms of H1N1 influenza A are fever (66.7%), dry cough (60.6%), cough with sputum (42.4%) and sore throat (36.4%). The laboratory tests in 24 cases (72.7%) were normal, while mild abnormal results were found in the remaining patients. All of the 33 cases were discharged according to the Standard of Diagnosis and Treatment of H1N1 Influenza A published by The Minister of Health, China. The period between 2-consecutive negative results in viral nucleic acid RT-PCR detection and the presenting symptom was 2 to 16 days and the period of hospitalization was 3 to 16 days.

CONCLUSION

The new type of H1N1 influenza A is characterized by mild symptoms, short period of hospitalization and good prognosis. All the patients can be cured, if they do not suffer from other severe chronic disease.

摘要

目的

回顾甲型H1N1流感的临床特征,为今后甲型H1N1流感的诊断和治疗提出临床实践建议。

方法

对2009年5月15日至6月22日在北京地坛医院住院的33例甲型H1N1流感患者进行研究,并用SPSS 11.0 for Windows对临床资料进行统计分析。

结果

33例患者中25例在一周内有美国、加拿大、日本等地旅行史;12例密切接触患者潜伏期为1至6天。甲型H1N1流感的主要症状为发热(66.7%)、干咳(60.6%)、咳痰(42.4%)和咽痛(36.4%)。24例(72.7%)实验室检查正常,其余患者有轻度异常结果。33例均按照中国卫生部发布的《甲型H1N1流感诊疗方案》出院。病毒核酸RT-PCR检测连续2次阴性结果与出现症状的间隔时间为2至16天,住院时间为3至16天。

结论

新型甲型H1N1流感具有症状轻、住院时间短、预后良好的特点。所有患者如无其他严重慢性疾病均可治愈。

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