Liang Lian-chun, Zhang Qiang, Yu Fei, Li Ai-xin, Pan Wen, Sheng Ai-juan, Wu Hao, Jin Rong-hua, Li Ning
Department of Infectious Diseases, Beijing Youan Hospital, Capital Medical College, Beijing 100069, China.
Zhonghua Yi Xue Za Zhi. 2010 Aug 3;90(29):2071-3.
To analyze the epidemiology and clinical characteristics of influenza A (H1N1).
A retrospective analysis was performed on the clinical data of 137 cases of influenza A (H1N1) admitted into our hospital during May to August 2009.
In the early stage, most cases were imported from the US, Australia, Canada and the UK. While in the later stage, most of them were secondary. The patients were mainly children and youngsters. And the most common clinical manifestations were fever (n = 108), cough (n = 93) and sore throat (n = 67) while the most common signs congestive throat (n = 99) and swelling tonsil (n = 46). The average fever period was 3.3 ± 1.5 days. The clinical symptoms vanished in 4.4 ± 1.9 days. And the average length of stay was 5.5 ± 2.1 days. Laboratory tests: the count of leukocytes declined while that of lymphocytes increased in 39 cases (39.5%). The test of influenza A (H1N1) nucleic acid was positive. The chest radiograph showed intensive pulmonary markings or patchy pneumonia-like signs.
the groups of patients using Chinese herbs, western medicine plus Chinese herbs, symptomatic relief and placebo showed no significant difference in fever period, recovery time and the negative-converting period of influenza A (H1N1) nucleic acid tests became negative.
Influenza A (H1N1) may be recessive or dominant. Despite a strong infectivity, the clinical symptoms are mild and the clinical course is self-limited, similar to the seasonal influenza.
分析甲型H1N1流感的流行病学及临床特征。
对2009年5月至8月我院收治的137例甲型H1N1流感患者的临床资料进行回顾性分析。
早期病例多从美国、澳大利亚、加拿大及英国输入，后期多为二代病例。患者以儿童及青少年为主。最常见的临床表现为发热（108例）、咳嗽（93例）、咽痛（67例），最常见的体征为咽喉充血（99例）、扁桃体肿大（46例）。平均发热期为3.3±1.5天，临床症状在4.4±1.9天消失，平均住院时间为5.5±2.1天。实验室检查：39例（39.5%）白细胞计数下降，淋巴细胞计数升高，甲型H1N1流感核酸检测阳性，胸部X线表现为肺纹理增粗或斑片状肺炎样改变。
使用中药组、西药加中药组、对症治疗组及安慰剂组在发热期、恢复时间及甲型H1N1流感核酸检测转阴时间方面差异无统计学意义。
甲型H1N1流感可能呈隐性或显性感染。尽管传染性强，但临床症状较轻，病程呈自限性，与季节性流感相似。
