[2009年甲型H1N1流感病毒在北京的病原学特征]

[Etiological characteristics of influenza A (H1N1) 2009 virus in Beijing].

作者信息

Huang Fang, Guo Jing, Cui Shu-juan, Lü Yan-ning, Gao Zhi-yong, Li Wei-hong, Yan Han-qiu, Qu Mei, Shi Wei-xian, Lu Gui-lan, Zhang Xin, Zhang Dai-tao, Tian Li-li, Qian Hai-kun, Yang Peng, Pang Xing-huo, Wang Quan-yi

机构信息

Beijing Center for Disease Control and Prevention, Beijing 100013, China.

出版信息

Zhonghua Liu Xing Bing Xue Za Zhi. 2010 May;31(5):494-6.

PMID:21163022

Abstract

OBJECTIVE

To analyze the results of detection on influenza A (H1N1) 2009 virus in Beijing from May 2009 to December 2009 and to understand the epidemiologic characteristics during the pandemic period.

METHODS

The study was conducted from the May 1 to December 27, 2009. A total of 101 852 throat swab samples were detected with the real-time RT-PCR assay by the Beijing Network Laboratory. Data was statistically analyzed.

RESULTS

9843 samples showed influenza A (H1N1) 2009 positive, with an overall positive rate as 9.66%. In terms of the positive rates, they were 2.85% from May to June, 3.32% from July to August and 8.35% from September to October. The peak month fell in November (29.67%) and December (24.33%). The positive rates among the following subpopulations were: 8.40% among the suspected cases, 4.75% among close contact cases, 11.46% among the influenza-like illness cases and 7.33% among the cluster cases with fever. Positive cases mainly fell in age groups 5 - 14 and 15 - 24. The ratio of male to female was 1.5:1.

CONCLUSION

During the pandemic period of influenza A (H1N1) 2009, positive cases gradually increased during May to November but slowly decreasing in December.

摘要

目的

分析2009年5月至12月北京市甲型H1N1流感病毒检测结果，了解大流行期间的流行病学特征。

方法

研究于2009年5月1日至12月27日进行。北京市网络实验室采用实时逆转录聚合酶链反应检测法对101852份咽拭子样本进行检测，并对数据进行统计学分析。

结果

9843份样本甲型H1N1流感病毒检测呈阳性，总体阳性率为9.66%。5月至6月阳性率为2.85%，7月至8月为3.32%，9月至10月为8.35%。11月（29.67%）和12月（24.33%）为发病高峰月。以下亚人群的阳性率分别为：疑似病例8.40%，密切接触者4.75%，流感样病例11.46%，发热聚集性病例7.33%。阳性病例主要集中在5至14岁和15至24岁年龄组。男女比例为1.5:1。