Center for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.
J Behav Ther Exp Psychiatry. 2010 Sep;41(3):185-90. doi: 10.1016/j.jbtep.2010.01.001. Epub 2010 Jan 7.
We conducted a study of a group therapy based on exposure and mindfulness in the treatment of irritable bowel syndrome (IBS). Out of 49 outpatients, most of whom were referred from gastroenterological clinics, 34 entered into the 10-week treatment. Patients were assessed before, immediately after and 6 months after treatment. The assessments consisted of a gastrointestinal symptom diary, self-report questionnaires covering quality of life, gastrointestinal specific anxiety, general functioning, and a psychiatric interview. At post-treatment, the mean reduction in symptoms was 41% and 50% of patients showed clinically significant improvement in symptom level. Patients also showed marked improvement on other outcome measures. Treatment gains were maintained at follow-up. The results support the use of exposure and mindfulness based strategies in the treatment of IBS, but further randomised studies are needed to confirm the efficacy of the treatment.
我们开展了一项基于暴露和正念的团体治疗研究,以治疗肠易激综合征(IBS)。在 49 名门诊患者中,大多数是从胃肠病诊所转来的,其中 34 名患者参加了为期 10 周的治疗。在治疗前、治疗结束时和治疗后 6 个月对患者进行评估。评估包括胃肠道症状日记、涵盖生活质量、胃肠道特定焦虑、一般功能和精神科访谈的自我报告问卷。治疗结束时,症状平均减轻 41%,50%的患者在症状水平上有明显改善。患者在其他结果测量上也有显著改善。随访时治疗效果得以维持。结果支持在 IBS 的治疗中使用暴露和正念策略,但需要进一步的随机研究来证实该治疗的疗效。