Brunel University, Uxbridge, Middlesex, UK.
Brunel University, Uxbridge, Middlesex, UK.
Int J Cardiol. 2010 Nov 19;145(2):337-339. doi: 10.1016/j.ijcard.2009.12.001. Epub 2010 Jan 15.
It has been previously shown that cardiac troponin (cTn) is released in response to prolonged endurance exercise. The influence of short-duration high-intensity exercise upon the release of cTn is not known. We examined cardiac troponin I (cTnI) release pre-, during and post-30 min of high-intensity running exercise in eight recreationally active males (age 29±3 years; VO2peak 53±11 ml kg min(-1)). Following exercise, cTnI increased in six of the eight participants. Four participants showed a minimal response (<0.05 µg/l) post-exercise. In contrast, two participants showed a progressive increase in cTnI (>0.1 µg/l) following exercise which peaked 3-4 h post-exercise. cTnI returned below the detection limit of the assay in all bar one of the participants 24 h post-exercise. These data are the first to show that cTnI can be released following short-duration high-intensity exercise. Clinicians should be aware that exercise-induced release of cTnI is not limited to prolonged endurance activity.
先前的研究表明，心肌肌钙蛋白（cTn）会在长时间的耐力运动后释放。但是，目前还不清楚短时间高强度运动对 cTn 释放的影响。我们研究了 8 名有规律运动的男性在 30 分钟高强度跑步运动前后即刻的肌钙蛋白 I（cTnI）释放情况（年龄 29±3 岁；峰值摄氧量 53±11 ml kg min(-1))。运动后，8 名参与者中有 6 名的 cTnI 增加。4 名参与者的运动后反应较小（<0.05 µg/l）。相比之下，2 名参与者的 cTnI 在运动后呈渐进性增加，在运动后 3-4 小时达到峰值。所有参与者除 1 人外，在 24 小时后 cTnI 均降至检测限以下。这些数据首次表明，cTnI 可以在短时间高强度运动后释放。临床医生应注意，cTnI 的运动诱导释放不仅限于长时间的耐力活动。
