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运动诱导肌钙蛋白释放。

Exercise-induced release of troponin.

机构信息

Division of Cardiology, Igias Melathron, Athens, Greece.

Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UK.

出版信息

Clin Cardiol. 2020 Aug;43(8):872-881. doi: 10.1002/clc.23337. Epub 2020 Jan 24.

Abstract

It is well established that regular physical activity reduces cardiovascular disease risk; however, numerous studies have demonstrated postexercise elevations in cardiac troponin (cTn), indicative of cardiac injury in apparently healthy individuals. The prevalence of these findings in different exercise settings and population groups, as well as potential underlying mechanisms and clinical significance of exercise-induced cTn release are not yet quite determined. The present review will discuss the cTn response to exercise in light of developing cTn assays and the correlation between postexercise cTn release and cardiac function. Additionally, recent data regarding the potential link between strenuous endurance exercise and its relationship with unfavorable cardiac effects in athletes, as well as the management of patients presenting at emergency care after sport events will be briefly reviewed.

摘要

众所周知,有规律的体育活动可降低心血管疾病风险;然而,许多研究表明,在看似健康的个体中,运动后心肌肌钙蛋白(cTn)升高,提示存在心脏损伤。这些发现在不同的运动环境和人群中的普遍性,以及运动引起的 cTn 释放的潜在机制和临床意义尚不完全确定。本综述将根据新的 cTn 检测方法的发展以及运动后 cTn 释放与心功能之间的相关性,讨论运动对 cTn 的影响。此外,还将简要回顾最近关于剧烈耐力运动与运动员不良心脏效应之间潜在联系的数据,以及在运动后出现紧急医疗情况的患者的管理。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d957/7403670/40d2a3c00a0c/CLC-43-872-g001.jpg

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