Instituto Oswaldo Cruz - FIOCRUZ, Av Brasil 4365, Rio de Janeiro, Brazil.
J Clin Virol. 2010 Mar;47(3):208-15. doi: 10.1016/j.jcv.2009.12.005. Epub 2010 Jan 18.
The 25th International Papillomavirus Conference was held in Malmo, Sweden, on May 8-14, 2009. The conference encompassed all areas of papillomavirus (PV) research, from clinical vaccinology to molecular biology. This review highlights some of the 237 presentations and 887 abstracts which were presented and summarizes sessions on prophylactic vaccines, screening, epidemiology and therapeutics. Important advances included identification of variants in four genes associated with HPV persistence, new HPV detection are likely new infections and not latency reactivation, and development of effective DNA vaccines that targets E6/E7 genes of HPV11. Also, many studies from different countries demonstrated that HPV vaccination provided sustained protection and substantial reduction of disease burden in both women and men, and in HIV-infected neonates. All the references cited are from the abstract book of the IPV Conference. See http://www.hpv2009.org/.
第 25 届国际乳头瘤病毒会议于 2009 年 5 月 8 日至 14 日在瑞典马尔默举行。会议涵盖了乳头瘤病毒（PV）研究的所有领域，从临床疫苗学到分子生物学。这篇综述突出了在 237 次演讲和 887 次摘要中介绍的部分内容，并总结了预防性疫苗、筛查、流行病学和治疗学方面的会议。重要进展包括鉴定与 HPV 持续存在相关的四个基因的变异体、新的 HPV 检测可能是新的感染而不是潜伏再激活，以及开发针对 HPV11 的 E6/E7 基因的有效 DNA 疫苗。此外，来自不同国家的许多研究表明，HPV 疫苗接种为女性和男性以及感染 HIV 的新生儿提供了持续的保护和疾病负担的大量减少。所有引用的参考文献均来自 IPV 会议摘要集。请访问 http://www.hpv2009.org/。
