[中医体质类型与高血压的关系]

[Relationships between constitutional types of traditional Chinese medicine and hypertension].

作者信息

Zhu Yan-bo, Wang Qi, Deng Qi-wei, Cai Jing, Song Xiao-hong, Yan Xue

机构信息

Department of Management, Beijing University of Chinese Medicine, Beijing 100029, China.

出版信息

Zhong Xi Yi Jie He Xue Bao. 2010 Jan;8(1):40-5.

PMID:20082757

Abstract

OBJECTIVE

To investigate the relationships between constitutional types of traditional Chinese medicine (TCM) and hypertension so as to provide epidemiological evidence for the theory of correlation between constitution and disease.

METHODS

A cross-sectional survey of TCM constitution data from a population of 7 782 from Beijng and 8 provinces of China (Jiangsu, Anhui, Gansu, Qinghai, Fujian, Jilin, Jiangxi, and Henan) was made in the study. The survey of TCM constitutions was performed by standardized TCM Constitution Questionnaire. Discriminatory analysis was used to judge the individual constitutional types including normal constitution, and qi deficiency, yang deficiency, yin deficiency, phlegm-dampness, damp-heat, blood stasis, qi stagnation and special constitutions. A multiple stepwise logistic regression analysis was applied to explore the significantly influential constitutional factors of hypertension.

RESULTS

After controlling several factors like gender, age, marital status, occupation, and educational background, three TCM constitutional factors according to different degrees of relative risks were entered into the multiple stepwise logistic regression model. The three factors were phlegm-dampness, yin deficiency and qi deficiency constitutions, and the odds ratio (OR) and 95% confidence interval (CI) were 2.00 [1.58, 2.55], 1.66 [1.33, 2.08] and 1.37 [1.13, 1.66] respectively. The main constitutional influential factors of hypertension in male patients were phlegm-dampness and yin deficiency constitutions, with OR and 95% CI of 1.61 [1.22, 2.14] and 1.60 [1.17, 2.19]. Phlegm-dampness, yin deficiency and qi deficiency constitutions were the main constitutional influential factors of hypertension in female patients. The OR and 95% CI were 2.80 [1.79, 4.39], 1.55 [1.13, 2.14] and 1.39 [1.05, 1.84] respectively. Phlegm-dampness constitution had more influence on hypertension in female patients than other constitution types.

CONCLUSION

Phlegm-dampness, yin deficiency, and qi deficiency constitutions are the main influential factors of hypertension. Hypertensive patients with different gender have different constitutional influential factors.

摘要

目的

探讨中医体质类型与高血压之间的关系，为体质与疾病相关性理论提供流行病学依据。

方法

本研究对来自北京及中国8个省份（江苏、安徽、甘肃、青海、福建、吉林、江西和河南）的7782人进行了中医体质数据的横断面调查。采用标准化中医体质问卷进行中医体质调查。运用判别分析判断个体体质类型，包括平和质以及气虚质、阳虚质、阴虚质、痰湿质、湿热质、血瘀质、气郁质和特禀质。应用多因素逐步logistic回归分析探讨高血压的显著影响体质因素。

结果

在控制性别、年龄、婚姻状况、职业和教育背景等因素后，根据相对危险度的不同程度，将3种中医体质因素纳入多因素逐步logistic回归模型。这3种因素分别为痰湿质、阴虚质和气虚质，比值比（OR）及95%置信区间（CI）分别为2.00 [1.58, 2.55]、1.66 [1.33, 2.08]和1.37 [1.13, 1.66]。男性高血压患者的主要体质影响因素为痰湿质和阴虚质，OR及95%CI分别为1.61 [1.22, 2.14]和1.60 [1.17, 2.19]。痰湿质、阴虚质和气虚质是女性高血压患者的主要体质影响因素，OR及95%CI分别为2.80 [1.79, 4.39]、1.55 [1.13, 2.14]和1.39 [1.05, 1.84]。痰湿质对女性高血压患者的影响大于其他体质类型。