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创伤中心治疗创伤前危及生命事件对严重创伤患者转院死亡率的重要性。

The importance of pre-trauma centre treatment of life-threatening events on the mortality of patients transferred with severe trauma.

机构信息

Unidade de Cuidados Intensivos Polivalente, Centro Hospitalar do Porto, Hospital de Santo António, 4099-001 Porto, Portugal.

出版信息

Resuscitation. 2010 Apr;81(4):440-5. doi: 10.1016/j.resuscitation.2009.12.014. Epub 2010 Jan 18.

DOI:10.1016/j.resuscitation.2009.12.014
PMID:20083331
Abstract

AIM

The benefit of a well organised trauma system is acknowledged but doubts remain concerning the optimal pre-hospital trauma care model. We hypothesise that the treatment of life-threatening events before arrival at trauma centre--either pre-hospital or first hospital--may be more relevant to decreasing mortality than shortening the time to trauma centre.

METHODS

A cohort of 727 trauma patients with life-threatening events--identified as airway, breathing, circulation or neurological disability--requiring transfer to a trauma centre were studied. Data on patient's characteristics, trauma features, and mortality were taken from a trauma registry. Patients were divided into 3 groups depending on the place of treatment of life-threatening events: pre-hospital, first hospital or trauma centre. Survival Kaplan-Meier curves and logistic regression were used to assess the effect of place of treatment of life-threatening events on mortality.

RESULTS

Patients from the pre-hospital and first hospital groups had 20% and 27% mortality respectively, compared to 38% among those whose life-threatening events were corrected only at the trauma centre. Logistic regression showed that patients whose life-threatening events were corrected only at the trauma centre had an odds of death 3.3 times greater than those from the pre-hospital group, adjusted for patient and trauma characteristics and time to trauma centre.

CONCLUSION

In trauma patients requiring transfer to a trauma centre, pre-hospital interventions to treat life-threatening events may significantly decrease mortality when compared to similar interventions performed later at the trauma centre.

摘要

目的

组织良好的创伤系统的益处已得到认可,但对于最佳院前创伤救治模式仍存在疑问。我们假设,在到达创伤中心之前(无论是在院前还是在第一家医院)处理危及生命的事件,可能比缩短到达创伤中心的时间更能降低死亡率。

方法

本研究纳入了 727 名存在危及生命的事件(定义为气道、呼吸、循环或神经功能障碍)需要转至创伤中心的创伤患者。从创伤登记处获取患者特征、创伤特征和死亡率的数据。根据危及生命的事件治疗地点将患者分为 3 组:院前、第一家医院或创伤中心。使用生存 Kaplan-Meier 曲线和逻辑回归评估危及生命的事件治疗地点对死亡率的影响。

结果

与仅在创伤中心纠正危及生命的事件的患者(38%)相比,院前和第一家医院组的患者死亡率分别为 20%和 27%。逻辑回归显示,在校正危及生命的事件时仅在创伤中心治疗的患者死亡的几率是院前组的 3.3 倍,调整了患者和创伤特征以及到达创伤中心的时间。

结论

在需要转至创伤中心的创伤患者中,与在创伤中心进行类似的干预相比,院前干预以治疗危及生命的事件可能显著降低死亡率。

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