Department of Otolaryngology-Head and Neck Surgery, Indiana University School of Medicine, Indianapolis, Indiana, USA.
J Voice. 2010 Nov;24(6):750-4. doi: 10.1016/j.jvoice.2009.04.005. Epub 2010 Jan 18.
The OmniGuide flexible carbon dioxide (CO(2)) laser can be readily used in the office but patient tolerance has not been established. The aim of this pilot study was to determine patient tolerance of the flexible CO(2) laser. As a reference point, the 585-nm pulsed-dye laser (PDL) was selected for comparison because it is the only office-based laser in which patient tolerance has specifically been studied.
Prospective pilot study involving office-based surgery candidates with benign laryngeal pathology. Via flexible laryngoscopy, half of each lesion was treated with the CO(2) laser and the remaining half with the PDL, alternating the order of the lasers (to account for potential thermal injury from the first laser) and blinding the patient to treatment. Patients rated their discomfort immediately after each laser treatment and then completed postoperative questionnaires for discomfort and voice quality.
Ten patients with benign laryngeal disease were included. All patients tolerated the office-based laser surgeries without difficulty. The CO(2) laser was extremely well tolerated, with mean pain and burning scores of 2.0 and 2.3, respectively, on a scale of 1-10 (10 being intolerable pain). Postoperative pain questionnaires demonstrated minimal discomfort after the laser treatment. Those with resolution of laryngeal disease had significant voice improvement.
Flexible CO(2) laser laryngeal surgery is well tolerated in an office-based setting.
奥米加导光臂二氧化碳（CO2）激光可以方便地在诊室使用，但患者的耐受程度尚未确定。本研究旨在确定患者对软性 CO2 激光的耐受程度。作为参考点，选择了 585nm 脉冲染料激光（PDL）进行比较，因为它是唯一一种已经专门研究过患者耐受程度的诊室激光。
前瞻性试点研究涉及有良性喉部病变的诊室手术候选者。通过软性喉镜，将每个病变的一半用 CO2 激光治疗，另一半用 PDL 治疗，交替激光顺序（以考虑到第一激光的潜在热损伤）并对患者进行治疗盲法。患者在每次激光治疗后立即对不适程度进行评分，然后完成术后疼痛和嗓音质量问卷。
10 例良性喉部疾病患者纳入研究。所有患者均能顺利耐受诊室激光手术。CO2 激光的耐受性极好，疼痛和烧灼感评分分别为 2.0 和 2.3（1-10 分，10 分为无法忍受的疼痛）。激光治疗后，术后疼痛问卷显示疼痛轻微。那些喉部疾病得到缓解的患者嗓音明显改善。
软性 CO2 激光喉部手术在诊室环境中具有良好的耐受性。
