Department of Otolaryngology-Head & Neck Surgery, Philadelphia College of Osteopathic Medicine, Philadelphia, Pennsylvania.
Department of Otolaryngology-Head & Neck Surgery, Drexel University College of Medicine, Philadelphia, Pennsylvania.
J Voice. 2014 Mar;28(2):262.e9-262.e12. doi: 10.1016/j.jvoice.2013.08.010. Epub 2013 Sep 26.
The 585-nm pulsed-dye laser (PDL) is used for in-office treatment of recurrent respiratory papillomatosis (RRP), premalignant/early malignant lesions, vascular lesions, and proliferative lesions of the larynx. Reported advantages of this technique include avoidance of general anesthesia, improved efficiency, lower overall cost, and treatment of the anterior commissure with minimal web formation. Our objective was to review our experience with office-based PDL procedures for laryngeal lesions.
Retrospective review.
A chart review of patients undergoing office-based PDL procedures of laryngeal lesions from the years 2005 to 2012.
Of 33 patients, 32 (97%) tolerated the procedure without complication. One patient experienced an anxiety attack and the procedure was aborted. There were no complications. The following pathologies were treated: vascular lesions (n = 10), RRP (n = 8), granuloma (n = 5), premalignant lesions (n = 5), benign mass (n = 2), amyloidosis (n = 1), and anterior web (n = 1). Six (19%) patients, all with vascular lesions, were treated successfully with the in-office PDL and no operating room (OR) procedures. All six patients reported complete resolution of symptoms at 6 months posttreatment. Twenty-six (81%) patients were treated with a combination of in-office PDL and OR procedures, most commonly for RRP (n = 8). Seventeen patients had complete resolution of their symptoms with in-office PDL and OR procedures.
PDL treatment is a safe, well-tolerated, effective, adjunctive therapy and may function as monotherapy in the treatment of selected laryngeal lesions.
585nm 脉冲染料激光(PDL)用于治疗复发性呼吸道乳头瘤病(RRP)、癌前/早期恶性病变、血管病变以及喉内增生性病变。该技术的优势包括避免全身麻醉、提高效率、降低总体成本以及最小化前联合粘连来治疗前联合。我们的目的是回顾我们在喉内病变门诊 PDL 治疗中的经验。
回顾性研究。
回顾分析 2005 年至 2012 年间在门诊接受 PDL 治疗喉内病变的患者的病历。
33 例患者中,32 例(97%)无并发症耐受该操作。1 例患者发生焦虑发作,手术中止。无并发症发生。共治疗以下病变:血管病变(n=10)、RRP(n=8)、肉芽肿(n=5)、癌前病变(n=5)、良性肿块(n=2)、淀粉样变性(n=1)和前联合粘连(n=1)。6 例(19%)患者均为血管病变,成功接受门诊 PDL 治疗,无需行手术室(OR)治疗。6 例患者均报告术后 6 个月时症状完全缓解。26 例(81%)患者采用门诊 PDL 联合 OR 治疗,最常见的病变为 RRP(n=8)。17 例患者门诊 PDL 联合 OR 治疗后症状完全缓解。
PDL 治疗是一种安全、耐受良好、有效的辅助治疗方法,在治疗某些特定的喉内病变时可能作为单一疗法。