Mpiga Mickoto R, Akue J-P, Bisvigou U, Mayi Tsonga S, Nkoghe D
Centre international de recherches médicales de Franceville (CIRMF), BP 769, Franceville, Gabon.
Bull Soc Pathol Exot. 2010 Feb;103(1):41-43. doi: 10.1007/s13149-009-0031-6.
The serological prevalence of Toxoplasma gondii was studied among 839 pregnant women in two hospitals from Franceville (Gabon), between May 2007 and December 2007. Specific T gondii IgG and IgM were measured by Enzyme Linked Fluorescent Assay (ELFA). Datation of the infection was carried out by avidity test. Fifty-six percent of women in this study were immunised compare to the 71% who were found as immunised in a previous study carried out fifteen years ago. 2.6% were found to be IgM positive. However, from the avidity test it was found that these infections occurred before pregnancy contact with cats and age increase this prevalence. The lack of information for pregnant women, the lack of continuous training for health personnel and lack of awareness about interpretation of laboratory diagnostic tests like avidity test in these hospitals reduce the level of counselling for women about T gondii.
2007年5月至2007年12月期间，在加蓬弗朗斯维尔的两家医院对839名孕妇进行了弓形虫血清学流行率研究。采用酶联荧光分析法（ELFA）检测特异性弓形虫IgG和IgM。通过亲和力试验确定感染时间。本研究中56%的女性有免疫力，而在15年前进行的一项先前研究中，发现有71%的女性有免疫力。发现2.6%的女性IgM呈阳性。然而，通过亲和力试验发现，这些感染发生在怀孕前接触猫之前，并且年龄增加了这种流行率。这些医院缺乏针对孕妇的信息、卫生人员缺乏持续培训以及对诸如亲和力试验等实验室诊断测试结果解读的认识不足，降低了对女性关于弓形虫的咨询水平。
