Instituto Nacional de Salud Pública, Centro de Investigaciones en Salud Poblacional, Avenida Universidad 655, Col. Santa María Ahuacatitlán, 62508 Cuernavaca, Morelos, México.
Cancer Causes Control. 2010 Apr;21(4):577-86. doi: 10.1007/s10552-009-9487-8. Epub 2010 Jan 19.
It has been suggested that both moderate-and vigorous-intensity physical activity reduces the risk of breast cancer. However, the effect of moderate-intensity physical activity on breast cancer risk has not been consistently evaluated by menopausal status and has not been evaluated in Mexican women.
To evaluate the effect of moderate-intensity physical activity (h/week and MET-h/week) on the risk of breast cancer by menopausal status in Mexican women.
A population-based case-control study was conducted in Mexico. One thousand incident cases and 1,074 matched controls to cases by 5 years of age, site and health institution participated in the study. Women provided information on health, diet and physical activity by means of an in-person interview. Anthropometric measurements and blood samples were obtained from all women. A conditional logistic regression model was used to assess this association.
Participating in moderate-intensity physical activity decreased the risk of BC in both pre- and postmenopausal women (OR = 0.96; 95% CI 0.92.-0.99; OR = 0.90; 95% CI 0.86-0.93, respectively) for every 3 h per week of moderate-intensity physical activity. There was a statistically significant modification effect by menopausal status (p = 0.009).
Strategies need to be identified that will engage women in physical activity programs.
有研究表明，中等强度和剧烈强度的身体活动均可降低乳腺癌风险。然而，中等强度身体活动对乳腺癌风险的影响并未根据绝经状态进行一致评估，也未在墨西哥女性中进行评估。
评估中等强度身体活动（每周小时数和每周代谢当量小时数）对墨西哥女性乳腺癌风险的影响与绝经状态的关系。
在墨西哥进行了一项基于人群的病例对照研究。1000 例病例和 1074 例与病例按年龄相差 5 岁、部位和医疗机构相匹配的对照参加了该研究。女性通过面对面访谈提供健康、饮食和身体活动信息。对所有女性进行了人体测量学测量和血液样本采集。采用条件逻辑回归模型评估这种关联。
每周进行 3 小时中等强度身体活动，可分别降低绝经前和绝经后女性的 BC 风险（OR = 0.96；95%CI 0.92.-0.99；OR = 0.90；95%CI 0.86-0.93）。绝经状态存在统计学显著的修饰效应（p = 0.009）。
需要确定可让女性参与身体活动计划的策略。
