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活检次数对从乳腺钼靶检查结果出具到乳腺癌组织病理学诊断之间延迟时间的影响。

The effect of the number of biopsies on the delay in the time from the delivery of mammography results to breast cancer histopathological diagnosis.

作者信息

Garduño-Alanis Adriana, Morales-González Lizbeth, Ángeles-Llerenas Angélica, Delgado-Ramírez José Zaim, Ortega-Olvera Carolina, Torres-Mejía Gabriela

机构信息

School of Nursing and Obstetrics, Autonomous University of the State of Mexico, Paseo Tollocan s/n, Esquina Jesús Carranza, Col. Moderna de la Cruz, C.P. 50180, Toluca, MEX., Mexico.

Research Department, Universidad de la Salud del Estado de México, Vialidad Toluca Atlacomulco 1946, Col. La Aviación, C.P. 50295, Toluca, MEX., Mexico.

出版信息

Cancer Causes Control. 2022 Nov;33(11):1355-1361. doi: 10.1007/s10552-022-01622-6. Epub 2022 Aug 27.

DOI:10.1007/s10552-022-01622-6
PMID:36029415
Abstract

PURPOSE

The delay in the time (in calendar days) from the delivery of mammography results to histopathological breast cancer (BC) diagnosis could be associated with more advanced clinical stages, a worse prognosis and higher mortality. Therefore, we assessed the association between the number of biopsies and the delay in the time (in calendar days) from the delivery of mammography results to histopathological BC.

METHODS

A survey was performed on 563 women aged between 35 and 69 years with histopathologically confirmed BC who attended 11 Mexican hospitals.

RESULTS

After adjusting for potential confounders, the odds of having a delay in the time (in calendar days) from the delivery of mammography results to histopathological BC diagnosis (≥ 60 days) among women with ≥ 3 biopsies were 2.99 times the odds of those who had only one biopsy (95% CI 1.35, 6.63).

CONCLUSION

The number of biopsies should be considered as a predictor of the time delay between the delivery of the mammography result and the diagnostic result.

摘要

目的

从乳腺钼靶检查结果出具到乳腺癌组织病理学诊断的时间延迟(以日历天数计)可能与更晚期的临床分期、更差的预后和更高的死亡率相关。因此,我们评估了活检次数与从乳腺钼靶检查结果出具到乳腺癌组织病理学诊断的时间延迟(以日历天数计)之间的关联。

方法

对563名年龄在35至69岁之间、组织病理学确诊为乳腺癌且就诊于11家墨西哥医院的女性进行了一项调查。

结果

在对潜在混杂因素进行校正后,活检次数≥3次的女性从乳腺钼靶检查结果出具到乳腺癌组织病理学诊断出现延迟(≥60天)的几率是仅进行1次活检的女性的2.99倍(95%置信区间1.35, 6.63)。

结论

活检次数应被视为乳腺钼靶检查结果出具与诊断结果之间时间延迟的一个预测因素。

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