[Analysis on the adverse event following immunization (AEFI) after supplementary immunization activity of measles attenuated live vaccine in Sichuan province in 2007-2008].

OBJECTIVE

To analyze the characteristic and regular patterns of AEFI after Supplementary Immunization Activity (SIAs) of Measles Attenuated Live Vaccine in Sichuan Province in 2007-2008, to discuss the safety of MV SIAs and measures of reducing occurrence of AEFI.

METHODS

The descriptive epidemiology analysis on related indexes were conducted.

RESULTS

59 cases of serious AEFI were reported in MV SIAs in 2007-2008. The incidence rate was 4.13/million dosage, and male was higher than female; The incidence between age groups was no significant statistics differences (chi2 = 0.53, P>0.05); people occurrencing serious AEFI within 2 days after vaccination accounted for 3/4. Allergic reaction dominated the clinical damage. Most of the cases were cured.

CONCLUSION

Incidence of serious AEFI after MV SIAs was low. It is safe to conduct MV SIAs. Children of all age groups should be observed within 2 day after vaccination. To guarantee the smooth conduct of MV SIAs, we should strengthen AEFI surveillance and improve the skill for handling with serious AEFI.