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[高强度辐射暴露对猴子脑功能的影响。辐射后脑生物电活动的变化]

[The effect of a high-intensity radiation exposure on the brain function of monkeys. The postradiation changes in brain bioelectrical activity].

作者信息

Legeza V I, Turlakov Iu S

出版信息

Radiobiologiia. 1991 Jan-Feb;31(1):97-106.

PMID:2008531
Abstract

In experiments with Macaca fascicularis it has been found that changes in the total bioelectric activity of the brain within the EEG range that occur during the first 60 min following whole-body irradiation with a dose of 45 Gy (6.5 Gy/s) are interrelated with the dynamics of nervous and psychic activity of the exposed animals, exhibit a definite stereotype of their development (disorganization of rhythms: generalized synchronization of biopotentials; and development of synchronous processes), and coincide in time with the main stages of the development of the clinical picture of the acute postirradiation period (noncoordinated stimulation, sopor or coma, and partial recovery).

摘要

在对猕猴进行的实验中发现,在以45 Gy(6.5 Gy/秒)的剂量对全身进行照射后的最初60分钟内,脑电图范围内大脑总生物电活动的变化与受照射动物的神经和精神活动动态相关,呈现出其发展的特定模式(节律紊乱:生物电位的普遍同步化;以及同步过程的发展),并且在时间上与急性辐射后时期临床表现发展的主要阶段(不协调刺激、嗜睡或昏迷以及部分恢复)相吻合。

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