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[高强度辐射暴露对猴子脑功能的影响。辐射后大脑生物电过程的中枢协调变化]

[Effect of a high-intensity radiation exposure on brain function in monkeys. Postradiation changes in central coordination of brain bioelectrical processes].

作者信息

Legeza V I, Turlakov Iu S

出版信息

Radiobiologiia. 1991 Mar-Apr;31(2):237-45.

PMID:2034804
Abstract

In experiments with Macaca fascicularis exposed to high-energy electrons (45 Gy, 6.5 Gy/s) revealed were early changes in the coherent spectrum of EEG semihemispheric leads. These changes were displayed by the increased interrelation between slow-wave fluctuations and decreased coherence within the mid- and high-frequency EEG-rhythms band. The relationship was noted between the changes observed and the clinical symptoms features of early radiation response as well as the dynamics of the CNS functions of exposed animals. Postirradiation changes in the intracellular bioelectric interaction are considered as one of the manifestations of the systemic response of the brain to the harmful effect of radiation.

摘要

在对食蟹猴进行高能电子(45 Gy,6.5 Gy/s)照射的实验中,发现脑电图半脑导联相干谱出现早期变化。这些变化表现为慢波波动之间的相互关系增加,以及中高频脑电图节律带内的相干性降低。观察到的这些变化与早期辐射反应的临床症状特征以及受照射动物中枢神经系统功能的动态变化之间存在关联。辐照后细胞内生物电相互作用的变化被认为是大脑对辐射有害作用的全身反应的表现之一。

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