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S-1联合放射治疗晚期侵犯胸壁的肺癌

[Treatment with S-1 and radiation therapy for advanced lung cancer invading chest wall].

作者信息

Furuichi Motohiko, Muramatsu Takashi, Shimamura Mie, Nishii Tatsuhiko, Takeshita Shinji, Ishimoto Shinichiro, Morooka Hiroaki, Sodeyama Masako, Sakurai Kenichi, Amano Sadao, Ohmori Ikko, Shiono Motomi

机构信息

Department of Surgery, Nihon University School of Medicine, Japan.

出版信息

Gan To Kagaku Ryoho. 2010 Jan;37(1):119-22.

Abstract

The patient was a 63-year-old man, who had been suffering from lung cancer with left chest wall invasion and contralateral pulmonary metastases. Due to the severe pain caused by this advanced lung cancer with poor performance status (PS), oxycodone was administered for treatment. Radiotherapy was used for local tumor control and oral S-1 was given as systemic chemotherapy. The local control rate (near CR) and the PS were improved effectively by this combination of palliative treatment. As a result, he was allowed to return home and followed as an outpatient. Our experience suggests that positive palliative treatment improves the quality of life (QOL) of patients and provides survival benefits.

摘要

该患者为一名63岁男性,患有肺癌并伴有左胸壁侵犯及对侧肺转移。由于这种晚期肺癌导致严重疼痛且身体状况较差(PS),给予羟考酮进行治疗。采用放疗控制局部肿瘤,并给予口服S-1进行全身化疗。通过这种姑息治疗联合方案,局部控制率(接近完全缓解)和身体状况得到有效改善。结果,他被允许回家并作为门诊患者进行随访。我们的经验表明,积极的姑息治疗可提高患者的生活质量(QOL)并带来生存益处。

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