Department of General Surgery, Beijing Chaoyang Hospital, Capital Medical University, Beijing, People's Republic of China.
Dis Colon Rectum. 2010 Feb;53(2):219-23. doi: 10.1007/DCR.0b013e3181b715b5.
Patients who undergo cylindrical abdominoperineal resection can have significant complications, especially those who require pelvic reconstruction using myocutaneous flaps. Reconstruction using a biomaterial may be a novel alternative. The purpose of this study is to report the initial results of pelvic reconstruction using human acellular dermal matrix after cylindrical abdominoperineal resection.
Between January 2008 and February 2009, pelvic floor reconstruction was performed in 12 consecutive patients who underwent cylindrical abdominoperineal resection for advanced ultralow rectal cancer.
Two weeks after the operation, primary complete healing of the perineal wound was seen in 11 patients. At a median follow-up of 8 months, there was no perineal wound breakdown, bulge, or herniation. One patient had an asymptomatic seroma, one patient had a perineal wound infection, and 4 patients had perineal pain that resolved.
Human acellular dermal matrix provided a safe alternative for the reconstruction of large pelvic defect in the patients after cylindrical abdominoperineal resection.
接受圆柱形经腹会阴切除术的患者可能会出现严重的并发症，特别是那些需要使用肌皮瓣进行骨盆重建的患者。使用生物材料进行重建可能是一种新的选择。本研究的目的是报告在圆柱形经腹会阴切除术后使用人去细胞真皮基质进行骨盆重建的初步结果。
在 2008 年 1 月至 2009 年 2 月期间，对 12 例接受圆柱形经腹会阴切除术治疗超低位直肠腺癌的患者进行了盆底重建。
术后 2 周，11 例患者会阴伤口一期完全愈合。中位随访 8 个月时，无会阴伤口破裂、隆起或疝。1 例患者出现无症状性血清肿，1 例患者会阴伤口感染，4 例患者会阴疼痛缓解。
人去细胞真皮基质为圆柱形经腹会阴切除术后患者的大型骨盆缺陷重建提供了一种安全的替代方法。
