Suppr超能文献

用于证明对局部麻醉剂过敏反应的剂量激发试验(DPT)。

DPT (dose provocative test) test for proving allergic reactions to local anaesthetics.

作者信息

Simjanovska Lj, Marsenić M, Simjanovski S

机构信息

Oral Surgery Department, Faculty of Dentistry, Skopje, R. Macedonia. buba

出版信息

Prilozi. 2009 Dec;30(2):239-48.

Abstract

To prove the existence of possible allergic reaction to local anaesthetic by the recommendations and experience of the current literature, an assortment or mosaic of complementary diagnostic tests is made by: anamnesis and a clinical picture and in vivo skin allergy tests - tests of the humeral and cellular immune response. Anamnesis and the clinical picture are mostly in metaphorical characteristics because we are not direct observers of the happenings and manifestations. If we use anaesthetics every day there is a possibility of side effects. The main aim is to determine the real persistence of hypersensitive reactions. For diagnosing the hypersensitive reactions in this task, in vivo tests were done on 50 examinees with plus (+) anamnesis for unwanted reactions from previous anesthetics applications (tooth extraction). The accent is put on the DPT (dose provocation test). Based on SAT allergic testing the percentage is 4.0%. We used the relative statement of the patient as support for the real picture of the event. The DPT test is considered the only in vivo test that may exclude the risk of allergic reaction, because of its specificity and high risk. Besides the negative results from DPT we cannot be absolutely sure and rely on the test results, including the results of anaesthetic application, because the risk of allergic reaction of patients who have been tested is not higher than that of the patients who have not been tested.

摘要

根据当前文献的建议和经验,为证明对局部麻醉剂可能存在过敏反应,需通过以下方式进行一系列或组合的补充诊断测试:问诊、临床表现以及体内皮肤过敏测试——体液和细胞免疫反应测试。问诊和临床表现大多具有隐喻性特征,因为我们并非事件和表现的直接观察者。如果我们每天使用麻醉剂,就有可能出现副作用。主要目的是确定过敏反应的实际持续性。为诊断本研究中的过敏反应,对50名有过(+)因先前使用麻醉剂(拔牙)出现不良反应的问诊记录的受检者进行了体内测试。重点在于DPT(剂量激发试验)。基于SAT过敏测试,阳性率为4.0%。我们将患者的相关陈述作为对事件真实情况的支持。DPT测试被认为是唯一可排除过敏反应风险的体内测试,因其特异性和高风险。除了DPT的阴性结果外,我们不能绝对确定并依赖测试结果,包括麻醉剂应用的结果,因为已测试患者的过敏反应风险并不高于未测试患者。

相似文献

2
[Allergic reactions to local anesthetics].[局部麻醉药的过敏反应]
Rev Esp Anestesiol Reanim. 1990 May-Jun;37(3):172-5.
10
Suspected allergy to local anaesthetics: follow-up in 135 cases.疑似局部麻醉剂过敏:135 例随访。
Acta Anaesthesiol Scand. 2010 May;54(5):536-42. doi: 10.1111/j.1399-6576.2009.02193.x. Epub 2010 Jan 6.

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验