Department of Gerontology, Faculty of Social Welfare and Health Sciences, University of Haifa, Haifa, Israel.
Int J Clin Pract. 2010 Jan;64(2):182-7. doi: 10.1111/j.1742-1241.2009.02251.x.
Patent foramen ovale (PFO) is common in asymptomatic adults, but imposes higher risk for transient ischaemic attack (TIA) or cerebral vascular accident (CVA). Trans-catheter closure of the PFO is now a common procedure in patients after cryptogenic CVA or TIA. No studies to date have assessed the psychological aspects of PFO closure.
To assess the level of psychological distress, quality of life and optimism in patients post-PFO closure in comparison with healthy age-matched controls.
A total of 89 patients who had undergone trans-catheter PFO closure and 60 age-matched controls were enrolled in the cross-sectional study. They answered demographic, health, quality of life, anxiety and depression and optimism questionnaires.
PFO patients and controls reported similar levels of quality of life, depression and anxiety, although the study group reported a higher level of optimism. An age x group effect appeared for depression, indicating that older controls were significantly more depressed than their counterparts in the study group and than the younger participants in both groups. Optimism significantly accounted for the variance of depression, anxiety and quality of life, and age significantly accounted for depression and quality of life, while group also significantly accounted for depression.
Post-PFO closure patients enjoy good psychological well-being and quality of life, and are more optimistic, which supports the view of optimism as a situational trait.
卵圆孔未闭（PFO）在无症状成年人中很常见，但会增加短暂性脑缺血发作（TIA）或脑卒中等风险。目前，经导管封堵 PFO 已成为隐源性卒中和 TIA 患者的常见治疗方法。但迄今为止，尚无研究评估 PFO 封堵的心理方面。
与年龄匹配的健康对照组相比，评估 PFO 封堵术后患者的心理困扰程度、生活质量和乐观程度。
共纳入 89 例行经导管 PFO 封堵术的患者和 60 名年龄匹配的对照组患者。他们回答了人口统计学、健康状况、生活质量、焦虑和抑郁以及乐观问卷。
PFO 患者和对照组报告的生活质量、抑郁和焦虑水平相似，但研究组报告的乐观程度更高。抑郁存在年龄 x 组的交互效应，表明对照组中的老年人比研究组中的同龄人以及两组中的年轻参与者抑郁程度更高。乐观程度显著解释了抑郁、焦虑和生活质量的差异，年龄显著解释了抑郁和生活质量的差异，而组间差异也显著解释了抑郁的差异。
PFO 封堵术后患者的心理幸福感和生活质量良好，且更乐观，这支持了乐观是一种情境特质的观点。
