Khan Aslam, Mittal Suneet, Sherrid Mark V
Division of Cardiology, St Luke's and Roosevelt Hospitals, Columbia University College of Physicians & Surgeons, New York, NY 10019, USA.
Anadolu Kardiyol Derg. 2009 Dec;9 Suppl 2:12-6.
Brugada syndrome is a genetic cause of sudden cardiac arrest characterized by abnormal electrocardiographic (ECG) pattern in the right precordial leads either at rest or after provocation. In this condition, sudden death may occur due to polymorphic ventricular tachycardia or ventricular fibrillation. In approximately 30% of patients, sudden cardiac arrest is the initial clinical manifestation of Brugada syndrome. Treatment strategies for Brugada syndrome are evolving. Currently, the implanted cardioverter defibrillator (ICD) is the only proven treatment for Brugada syndrome. Candidates for ICD include patients include those with the type 1 ECG pattern or who have been successfully resuscitated from sudden death or have had unexplained syncope.
Brugada综合征是一种导致心脏骤停的遗传性疾病，其特征是右胸前导联在静息或激发后出现异常心电图（ECG）模式。在这种情况下，可能会因多形性室性心动过速或心室颤动而发生猝死。在大约30%的患者中，心脏骤停是Brugada综合征的初始临床表现。Brugada综合征的治疗策略正在不断发展。目前，植入式心脏复律除颤器（ICD）是Brugada综合征唯一经证实有效的治疗方法。ICD的适用患者包括具有1型ECG模式的患者，或已从猝死中成功复苏或有不明原因晕厥的患者。
