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[卵胞浆内单精子注射治疗男性不育症]

[Intracytoplasmic sperm injection for treatment of male infertility].

作者信息

Tsagareishvili G G, Khonelidze N L, Koiava M A, Osidze K R

出版信息

Georgian Med News. 2009 Dec(177):38-40.

Abstract

The results of 84 consecutive couples who underwent 94 cycles of in-vitro fertilization (IVF) augmented with intracytoplasmic sperm injection (ICSI) were analyzed. Inclusion criteria were previous total failed fertilization or unsuitable sperm parameters for conventional IVF. The rate of diploid fertilization was 61,7%; the implantation rate per embryo was 12,0% and the ongoing pregnancy rate per transfer was 30,0%. None of the sperm parameters of the original or processed semen sample were correlated with ICSI outcome. Conversely, female age and basal serum concentrations of follicle stimulating hormone (FSH) had a significant impact on implantation and pregnancy rates. ICSI has become a very successful therapy in overcoming different types of male infertility.

摘要

对连续84对接受94个周期体外受精(IVF)并辅以卵胞浆内单精子注射(ICSI)的夫妇的结果进行了分析。纳入标准为既往完全受精失败或常规IVF的精子参数不合适。二倍体受精率为61.7%;每个胚胎的着床率为12.0%,每次移植的持续妊娠率为30.0%。原始或处理后的精液样本的精子参数均与ICSI结果无关。相反,女性年龄和基础血清促卵泡生成素(FSH)浓度对着床率和妊娠率有显著影响。ICSI已成为克服不同类型男性不育症的一种非常成功的治疗方法。

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