提上睑肌位移可预测甲状腺相关眼病的眼睑迟滞和兔眼。
Levator excursion as a predictor of both eyelid lag and lagophthalmos in thyroid eye disease.
机构信息
Weill Cornell Department of Ophthalmology, New York Presbyterian Hospital, New York, New York 10021, USA.
出版信息
Ophthalmic Plast Reconstr Surg. 2010 Jan-Feb;26(1):7-10. doi: 10.1097/IOP.0b013e3181b8e08d.
PURPOSE
To evaluate the relationship between levator excursion and both eyelid lag and lagophthalmos in thyroid eye disease.
METHODS
We retrospectively reviewed 104 eyelids of 52 thyroid eye disease patients over a 9-month interval by measuring levator function (mm), eyelid lag (0-4+) and lagophthalmos (mm).
RESULTS
Lower levator excursion is associated with higher eyelid lag scores (p < 0.001) and with greater degrees of lagophthalmos (p < 0.001). Both associations were upheld after adjustment for upper eyelid margin reflex distance and Hertel exophthalmometry (p < 0.0001). For every 1-mm decrease in levator function, eyelid lag score increases on average by 0.29 and lagophthalmos increases on average by 0.23 mm.
CONCLUSIONS
Diminished levator excursion is associated with increasing levels of eyelid lag and lagophthalmos. Levator excursion is an important clinical measurement in thyroid eye disease patients and may replace eyelid lag grading and lagophthalmos as a more accurate indicator of eyelid retraction in thyroid eye disease.
目的
评估甲状腺眼病中提上睑肌活动度与眼睑迟滞和睑裂闭合不全的关系。
方法
我们通过测量提上睑肌功能（mm）、眼睑迟滞（0-4+）和睑裂闭合不全（mm），回顾性分析了 9 个月内 52 例甲状腺眼病患者的 104 只眼睑。
结果
较低的提上睑肌活动度与较高的眼睑迟滞评分（p<0.001）和更大程度的睑裂闭合不全（p<0.001）相关。在上睑缘反射距离和 Hertel 突眼计校正后，这两种相关性仍然成立（p<0.0001）。提上睑肌功能每降低 1mm，眼睑迟滞评分平均增加 0.29mm，睑裂闭合不全平均增加 0.23mm。
结论
提上睑肌活动度降低与眼睑迟滞和睑裂闭合不全程度的增加有关。提上睑肌活动度是甲状腺眼病患者的重要临床测量指标，可能替代眼睑迟滞分级和睑裂闭合不全，作为甲状腺眼病中眼睑退缩更准确的指标。
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