Desai Akruti, Singh Pallavi, Rootman Dan, Naik Milind N
Ophthalmic Plastic Surgery Service, Shantilal Shanghvi Eye Institute, Mumbai, Maharashtra, India.
Jules Stein Eye Institute, UCLA, Los Angeles, USA.
Indian J Ophthalmol. 2025 Feb 1;73(2):164-172. doi: 10.4103/IJO.IJO_748_24. Epub 2024 Dec 27.
Graves' disease, a common autoimmune disorder, characteristically presents with upper eyelid retraction, causing significant functional and cosmetic concerns for affected individuals. The management of Graves' upper eyelid retraction has evolved significantly over recent years, with various surgical and non-surgical interventions. An ideal procedure is predictable and easily repeatable. This review provides a comprehensive overview of the contemporary approaches to managing Graves' upper eyelid retraction, encompassing both traditional and emerging techniques. It critically evaluates the surgical options for correcting Graves' upper eyelid retraction to achieve the desired eyelid contour, eyelid crease, tarsal platform show, and brow fat span. Their comparative effectiveness is meticulously explored, offering clinicians valuable insights into treatment selection. Moreover, this review also underscores combined orbital decompression with levator recession. Additionally, advancements in non-invasive modalities, including botulinum toxin, triamcinolone acetate injections, and hyaluronic acid fillers are discussed in detail. This review aims to facilitate informed decision-making and improve the overall outcomes for individuals affected by Graves' disease-associated upper eyelid retraction.
格雷夫斯病是一种常见的自身免疫性疾病，其特征表现为上睑退缩，给患者带来严重的功能和美容问题。近年来，格雷夫斯病上睑退缩的治疗方法有了显著进展，包括各种手术和非手术干预措施。理想的手术方法应具有可预测性且易于重复。本综述全面概述了当代治疗格雷夫斯病上睑退缩的方法，涵盖传统技术和新兴技术。它严格评估了矫正格雷夫斯病上睑退缩以实现理想的眼睑轮廓、睑皱襞、睑板平台显露和眉脂肪间距的手术选择。对它们的相对有效性进行了细致探讨，为临床医生在治疗选择方面提供了有价值的见解。此外，本综述还强调了眼眶减压联合提上睑肌后退术。此外，还详细讨论了非侵入性治疗方法的进展，包括肉毒杆菌毒素、醋酸曲安奈德注射和透明质酸填充剂。本综述旨在促进明智的决策制定，并改善格雷夫斯病相关上睑退缩患者的总体治疗效果。
