Barr A E, Diamond B E, Wade C K, Harashima T, Pecorella W A, Potts C C, Rosenthal H, Fleiss J L, McMahon D J
Department of Rehabilitation Services, Hospital for Special Surgery, New York.
Arch Phys Med Rehabil. 1991 Apr;72(5):315-9.
In a multiinstitutional collaborative study, we ascertained the interevaluator and intraevaluator reliability of six physical therapists who performed assessment measures on 36 boys (11.7 +/- 3.9 years) with Duchenne or Becker muscular dystrophy. Upper and lower extremities were evaluated by manual muscle testing for function, range of motion, and strength. The data were analyzed using intraclass correlation coefficients (ICCs). For the interevaluator phase, ICCs were as follows: average muscle strength, .90; range of motion, .76; and upper extremity functional performance, .58. For the intraevaluator phase, corresponding ICCs were .80 to .96; .33 to .97; .34 to 1.00. Our results confirm and extend observations by others that these assessment measures are sufficiently reliable for use in a multiinstitutional collaborative effort. Such results can be used to design clinical trials that have sufficient statistical power to detect changes in the rate of disease progression. Investigators planning clinical trials in a multiinstitutional collaborative setting should first standardize the assessment methods, provide evaluator training, and document reliability.
在一项多机构合作研究中，我们确定了6名物理治疗师对36名患有杜氏或贝克型肌营养不良症的男孩（11.7±3.9岁）进行评估测量时的评估者间和评估者内信度。通过手法肌力测试对上肢和下肢的功能、活动范围和力量进行评估。使用组内相关系数（ICC）分析数据。在评估者间阶段，ICC如下：平均肌肉力量为0.90；活动范围为0.76；上肢功能表现为0.58。在评估者内阶段，相应的ICC为0.80至0.96；0.33至0.97；0.34至1.00。我们的结果证实并扩展了其他人的观察结果，即这些评估措施在多机构合作中使用具有足够的可靠性。这些结果可用于设计具有足够统计效力以检测疾病进展速度变化的临床试验。计划在多机构合作环境中开展临床试验的研究人员应首先规范评估方法，提供评估者培训，并记录信度。
