杜氏肌营养不良症男孩的支撑站立
Supported Standing in Boys With Duchenne Muscular Dystrophy.
作者信息
Townsend Elise L, Bibeau Christine, Holmes Tara M
机构信息
Department of Physical Therapy (Dr Townsend), School of Health and Rehabilitation Sciences, MGH Institute of Health Professions, Boston, Massachusetts; Department of Physical and Occupational Therapy (Dr Townsend) and Clinical Research Center (Ms Holmes), Massachusetts General Hospital, Boston, Massachusetts; Department of Rehabilitation (Dr Bibeau), Winchester Hospital, Winchester, Massachusetts.
出版信息
Pediatr Phys Ther. 2016 fall;28(3):320-9. doi: 10.1097/PEP.0000000000000251.
PURPOSE
To evaluate the safety, tolerability, and efficacy of supported standing in a small sample of boys with Duchenne muscular dystrophy (DMD).
METHODS
Four 12- to 15-year-old boys with DMD engaged in a home-based supported standing program for 6 to 12 months. A single-subject design was employed to examine muscle length. Bone mineral density was assessed at 4-month intervals using dual-energy x-ray absorptiometry.
RESULTS
Upright, sustained supported standing was tolerated in 3 of the 4 boys. Mean weekly stand times ranged from 1.3 to 3.3 hours. Improved hip or knee flexor muscle length was seen in 3 of the 4 boys. No boys showed improved plantar flexor muscle length or increased lumbar bone mineral density.
CONCLUSIONS
Findings offer preliminary empirical evidence addressing the safety, tolerability, and efficacy of standing in boys with DMD. Additional research with an emphasis on better program adherence is indicated.
目的
评估杜氏肌营养不良症（DMD）男孩小样本中支撑站立的安全性、耐受性和有效性。
方法
四名12至15岁的DMD男孩参与了一项为期6至12个月的居家支撑站立计划。采用单受试者设计来检查肌肉长度。每隔4个月使用双能X线吸收法评估骨密度。
结果
4名男孩中有3名耐受直立、持续的支撑站立。平均每周站立时间为1.3至3.3小时。4名男孩中有3名的髋部或膝部屈肌长度得到改善。没有男孩的跖屈肌长度得到改善或腰椎骨密度增加。
结论
研究结果为DMD男孩站立的安全性、耐受性和有效性提供了初步的实证证据。表明需要进行更多强调更好的计划依从性的研究。
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