Department of Ophthalmology, Aichi Medical University, Nagakute, Aichi, Japan.
Ophthalmic Plast Reconstr Surg. 2010 Jan-Feb;26(1):46-8. doi: 10.1097/IOP.0b013e3181b8c4b3.
The authors report a rare case of hemangiopericytoma-solitary fibrous tumor of the eyelid. A 35-year-old male presented with approximately 1-year history of a painless and slow growing mass on his right lower eyelid, which rapidly grew in size over the last few months. The size of the lesion and the location resulted in secondary mechanical ectropion at presentation. The tumor was excised and was found to be a "hemangiopericytoma-solitary fibrous tumor" based on both histopathological and immunohistochemical examinations. Immunohistochemically, the tumor was positive for CD34 and Vimentin but negative for S100 protein and smooth muscle actin. Although initial tumor removal was complete, the patient required a subsequent operation for his residual ectropion. Despite the lesion being large at presentation, surgical intervention resulted in good functional and cosmetic outcome.
作者报告了一例罕见的眼睑血管外皮细胞瘤-孤立性纤维瘤病例。一名 35 岁男性因右侧下眼睑无痛性、缓慢生长的肿块就诊，肿块在过去几个月内迅速增大。病变的大小和位置导致就诊时出现继发性机械性眼睑外翻。肿瘤被切除，根据组织病理学和免疫组织化学检查，发现为“血管外皮细胞瘤-孤立性纤维瘤”。免疫组化显示，肿瘤阳性表达 CD34 和波形蛋白，但阴性表达 S100 蛋白和平滑肌肌动蛋白。尽管初始肿瘤切除完全，但患者仍需进行后续手术以矫正残余的眼睑外翻。尽管病变在就诊时较大，但手术干预取得了良好的功能和美容效果。
