Hori Emiko, Kurimoto Masanori, Fukuda Osamu, Takahashi Chiaki, Nagai Shoichi, Oya Takeshi, Endo Shunro
Department of Neurosurgery, Saito Memorial Hospital, Niigata, Japan.
Brain Tumor Pathol. 2007;24(1):31-4. doi: 10.1007/s10014-006-0212-y. Epub 2007 May 25.
We describe a case of an intracranial solitary fibrous tumor that recurred three times consecutively in an 11-year period. A 72-year-old man presented with a headache and gait disturbance. Magnetic resonance imaging (MRI) revealed a dumbbell tumor at the left tentorium. The tumor was removed but recurred. The first diagnosis was hemangiopericytoma, but all specimens showed a "patternless pattern" and few reticulin fibers, which features were not compatible with hemangiopericytoma. All tumors showed immunoreactivity for CD34 and bcl-2. These results point to a solitary fibrous tumor (SFT) and not to hemangiopericytoma. We present here a hypercellular spindle-cell tumor that was very similar to hemangiopericytoma but is better diagnosed as SFT.
我们描述了一例颅内孤立性纤维瘤,该肿瘤在11年期间连续复发三次。一名72岁男性出现头痛和步态障碍。磁共振成像(MRI)显示左侧小脑幕有一个哑铃形肿瘤。肿瘤被切除但复发。最初诊断为血管外皮细胞瘤,但所有标本均显示“无模式模式”且网状纤维较少,这些特征与血管外皮细胞瘤不符。所有肿瘤对CD34和bcl-2均呈免疫反应性。这些结果表明是孤立性纤维瘤(SFT)而非血管外皮细胞瘤。我们在此呈现的是一种细胞增多的梭形细胞瘤,它与血管外皮细胞瘤非常相似,但更好地诊断为SFT。