Oncology Service, Wills Eye Institute, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA.
Ophthalmic Plast Reconstr Surg. 2010 Jan-Feb;26(1):48-50. doi: 10.1097/IOP.0b013e3181b8c607.
A healthy, 17-year-old boy presented with a 2-month history of an epibulbar mass on the left eye. Slit lamp examination showed an amelanotic, translucent, round, well-circumscribed, superonasal subconjunctival nodule. On ultrasound biomicroscopy, the tumor was acoustically hollow. The lesion was excised intact, and cryotherapy was applied to the surrounding conjunctiva. Histopathologic examination revealed a tumor composed of spindle cells with slender cytoplasmic processes and bland cigar-shaped nuclei, consistent with schwannoma. Immunohistochemistry showed positivity for S100 protein. The patient had no signs of neurofibromatosis. There was no tumor recurrence after 18 months. This case shows that conjunctival schwannoma can present as a translucent, well-circumscribed subconjunctival mass.
一位 17 岁健康男孩,左眼出现 2 个月的眶周肿块。裂隙灯检查显示,一个无黑色素、半透明、圆形、边界清楚的超鼻侧球结膜下小结节。超声生物显微镜检查显示,肿瘤呈声学空化。肿瘤完整切除,并对周围结膜进行冷冻治疗。组织病理学检查显示,肿瘤由梭形细胞组成,细胞浆细长,细胞核呈温和的雪茄形,符合神经鞘瘤。免疫组化显示 S100 蛋白阳性。患者无神经纤维瘤病的迹象。18 个月后无肿瘤复发。本例表明,结膜神经鞘瘤可表现为半透明、边界清楚的球结膜下肿块。