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一名12岁男孩的眼球表面神经鞘瘤:病例报告及文献复习

Epibulbar schwannoma in a 12-year-old boy: A case report and review of literature.

作者信息

Nair Akshay Gopinathan, Kaliki Swathi, Mishra Dilip Kumar, Dave Tarjani Vivek, Naik Milind N

机构信息

Institute for Eye Cancer, L.V. Prasad Eye Institute, Hyderabad, Telangana, India.

出版信息

Indian J Ophthalmol. 2015 Jul;63(7):620-2. doi: 10.4103/0301-4738.167106.

Abstract

Schwannomas are benign, encapsulated, primary neurilemmal tumors composed of proliferating Schwann cells. Schwannomas are commonly seen in the orbit, but are rare on the epibulbar surface. Herein, we report a case of a 12-year-old boy who presented to us with a slow-growing painless subconjunctival mass in the left eye. There was no intraocular extension of the mass and intra-operatively, the mass could be clearly delineated and was excised off the underlying sclera. Histopathological examination of the mass showed typical features of schwannoma and immunohistochemistry helped to confirm the diagnosis. There was no recurrence of the lesion observed at follow-up 26 months after surgery. Here, we describe this uncommon tumor and review the available literature. Although rare, an epibulbar schwannoma should be considered in the differential diagnosis of an amelanotic, painless subconjunctival nodular mass. Excision of the lesion is the recommended treatment.

摘要

施万细胞瘤是由增生的施万细胞组成的良性、有包膜的原发性神经鞘膜肿瘤。施万细胞瘤常见于眼眶,但在眼球表面很少见。在此,我们报告一例12岁男孩,其左眼出现一个生长缓慢、无痛的结膜下肿块。肿块未向眼内扩展,术中肿块可清晰界定,并从下方巩膜切除。肿块的组织病理学检查显示施万细胞瘤的典型特征,免疫组织化学有助于确诊。术后26个月随访未观察到病变复发。在此,我们描述这种罕见肿瘤并回顾现有文献。尽管罕见,但在鉴别诊断无色素、无痛的结膜下结节状肿块时应考虑眼球表面施万细胞瘤。推荐的治疗方法是切除病变。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9691/4652257/ec7582f82bc1/IJO-63-620-g001.jpg

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