Laboratory for Conservation and Utilization of Bio-Resources, and Key Laboratory for Microbial Resources of the Ministry of Education, Yunnan University, Kunming 650091, People's Republic of China.
Appl Microbiol Biotechnol. 2010 Mar;86(1):11-7. doi: 10.1007/s00253-009-2427-4. Epub 2010 Jan 21.
Several bacterial species are capable of using nicotine, the main alkaloid in tobacco plants, as a substrate for growth. The dominant species include members of two genera, Pseudomonas and Arthrobacter. The degradation pathway and genetic structure of nicotine catabolism in Arthrobacter nicotinovorans were recently reviewed (Brandsch Appl Microbiol Biotechnol 69:493-498, 2006). Here, we present up-to-date information on biodegradation of nicotine by Pseudomonas spp. Species in this genus capable of degrading nicotine are summarized and analyzed phylogenetically. Their metabolic intermediates and nicotine degradation-related genes were summarized, and the nicotine-biotransformation pathways were compared and discussed.
有几种细菌能够利用尼古丁（烟草植物中的主要生物碱）作为生长的底物。主要的物种包括假单胞菌属和节杆菌属的两个属的成员。尼古丁分解代谢在节杆菌属尼古丁降解菌中的降解途径和遗传结构最近被综述（Brandsch Appl Microbiol Biotechnol 69:493-498, 2006）。在这里，我们提供了有关假单胞菌属物种生物降解尼古丁的最新信息。总结并分析了该属中能够降解尼古丁的物种。总结了它们的代谢中间产物和与尼古丁降解相关的基因，并比较和讨论了尼古丁生物转化途径。
