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宫颈息肉的临床病理研究。

Clinico-pathological study of cervical polyps.

机构信息

Department of Obstetrics and Gynaecology, Barnet and Chase Farm Hospitals NHS Trust, Chase Farm Hospital, The Ridgeway, Enfield EN2 8JL, UK.

出版信息

Arch Gynecol Obstet. 2010 Nov;282(5):535-8. doi: 10.1007/s00404-010-1364-x. Epub 2010 Jan 21.

Abstract

OBJECTIVE

To determine the incidence of malignancy in cervical polyps and determine the effect of age and parity on clinical presentation.

METHODS

A retrospective analysis of histological diagnosis and demographic information relating to 294 polyps was undertaken. Comparison was made between premenopausal and postmenopausal women as well as women with and without recurrent polyps.

RESULTS

There was no case of malignancy. Majority of the women were parous (71.8%), asymptomatic (65.9%) and had their polyps removed in the outpatient setting (69.9%). The recurrence rate was 12.6%. The predominant symptom was IMB/PCB. Women with recurrent polyps were 10 times more likely to be parous (OR = 10.1, 95% CI 1.4-74.8), 7.9 times more likely to have symptoms (OR = 7.9, 95% CI 3.5-17.1) and 4.8 times more likely to have polyps removed under general anaesthesia (OR = 4.8, 95% CI 2.4-9.9). Postmenopausal women were 2.2 times more likely to have symptoms (OR = 2.2, 95% CI 1.6-4.7) and 1.7 times more likely to have general anaesthesia (OR = 1.7, 95% CI 1.0-3.1).

CONCLUSION

Cervical polyps are mainly benign, asymptomatic lesions and recur in about 12.6% of women. They are more likely to be symptomatic in postmenopausal women.

摘要

目的

确定宫颈息肉的恶性肿瘤发生率,并确定年龄和产次对临床表现的影响。

方法

对 294 例息肉的组织学诊断和人口统计学信息进行回顾性分析。比较了绝经前和绝经后妇女、以及有无复发性息肉的妇女之间的差异。

结果

没有恶性肿瘤病例。大多数妇女是多产妇(71.8%)、无症状(65.9%),并在门诊环境下切除息肉(69.9%)。复发率为 12.6%。主要症状是 IMB/PCB。复发性息肉的妇女多产的可能性是对照组的 10 倍(OR=10.1,95%CI 1.4-74.8),有症状的可能性是对照组的 7.9 倍(OR=7.9,95%CI 3.5-17.1),全麻下切除息肉的可能性是对照组的 4.8 倍(OR=4.8,95%CI 2.4-9.9)。绝经后妇女出现症状的可能性是对照组的 2.2 倍(OR=2.2,95%CI 1.6-4.7),全麻的可能性是对照组的 1.7 倍(OR=1.7,95%CI 1.0-3.1)。

结论

宫颈息肉主要是良性、无症状的病变,约 12.6%的妇女会复发。绝经后妇女更有可能出现症状。

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