Sidera Aikaterini, Matalliotakis Michail, Tsakiridis Ioannis, Matalliotaki Charoula, Krithinakis Konstantinos, Dagklis Themistoklis, Mamopoulos Apostolos M, Kalogiannidis Ioannis A
Third Department of Obstetrics and Gynaecology, Aristotle University of Thessaloniki, Thessaloniki, GRC.
Department of Obstetrics and Gynaecology, Venizeleio General Hospital, Heraklion, GRC.
Cureus. 2025 Jan 6;17(1):e77015. doi: 10.7759/cureus.77015. eCollection 2025 Jan.
Cervical polyps (CPs) and endometrial polyps (EPs) are common gynecological conditions worldwide. Understanding the distribution of benign and malignant pathologies in women with these polyps is clinically significant. The coexistence of these conditions underscores their complexity, requiring an inclusive and detailed approach to diagnosis and management. This study aimed to investigate the distribution of coexisting pathologies in women with CPs and EPs.
This retrospective study analyzed records from 2000 to 2020 at the Department of Obstetrics and Gynecology at Venizeleio General Hospital of Heraklion, Crete, and the Third Department of Obstetrics and Gynecology, School of Medicine, Faculty of Health Sciences, Aristotle University of Thessaloniki, Greece.
From a total sample of 3,490 women, 772 women were diagnosed with one or more polyps; 343 (9.9%) had CPs, and 488 (14%) had EPs. Benign pathologies, such as cervicitis, adenomyosis, paraovarian cysts, and fibroids, were strongly associated with the presence of CPs. Regarding EPs, a positive statistical relationship was present between them and serous cystadenomas (p=0.005), cervicitis (p<0.001), adenomyosis (p=0.001), paraovarian cysts, and more than five fibroids (p<0.001). Endometrial polyps were strongly (p<0.001) correlated to endometrial hyperplasia with or without atypia. The occurrence of EPs and CPs appeared to decrease with age. Further analyses revealed a strong positive correlation between EPs and endometrial cancer (p=0.006). Endometrial polyps were strongly (p<0.001) correlated to endometrial hyperplasia with or without atypia. The occurrence of EPs and CPs appeared to decrease with age. Further analyses revealed a strong positive correlation between EPs and endometrial cancer (p=0.006).
There appears to be a correlation between EPs/CPs and other gynecological pathologies. Comprehensive evaluation and further longitudinal studies are therefore crucial for patients with polyps, as they may be at higher risk for coexisting benign and potentially malignant conditions.
宫颈息肉（CPs）和子宫内膜息肉（EPs）是全球常见的妇科疾病。了解患有这些息肉的女性中良性和恶性病变的分布情况具有临床意义。这些疾病的共存凸显了它们的复杂性，需要采用全面且详细的诊断和管理方法。本研究旨在调查患有CPs和EPs的女性中共存病变的分布情况。
这项回顾性研究分析了希腊克里特岛伊拉克利翁维尼泽利奥综合医院妇产科以及希腊塞萨洛尼基亚里士多德大学健康科学学院医学院第三妇产科2000年至2020年的记录。
在总共3490名女性样本中，772名女性被诊断患有一种或多种息肉；343名（9.9%）患有CPs，488名（14%）患有EPs。良性病变，如宫颈炎、子宫腺肌病、卵巢旁囊肿和子宫肌瘤，与CPs的存在密切相关。关于EPs，它们与浆液性囊腺瘤（p = 0.005）、宫颈炎（p < 0.001）、子宫腺肌病（p = 0.001）、卵巢旁囊肿以及超过五个子宫肌瘤（p < 0.001）之间存在正相关的统计关系。子宫内膜息肉与有或无不典型增生的子宫内膜增生密切相关（p < 0.001）。EPs和CPs的发生率似乎随年龄增长而降低。进一步分析显示EPs与子宫内膜癌之间存在强正相关（p = 0.006）。子宫内膜息肉与有或无不典型增生的子宫内膜增生密切相关（p < 0.001）。EPs和CPs的发生率似乎随年龄增长而降低。进一步分析显示EPs与子宫内膜癌之间存在强正相关（p = 0.006）。
EPs/CPs与其他妇科病变之间似乎存在相关性。因此，对于患有息肉的患者，全面评估和进一步的纵向研究至关重要，因为他们可能面临共存的良性和潜在恶性疾病的更高风险。
