Department of Anesthesia, Social Insurance Sagamino Hospital, 1-2-30 Futinobe, Sagamihara, Kanagawa, 229-0006, Japan.
J Anesth. 2010 Apr;24(2):173-6. doi: 10.1007/s00540-009-0848-y. Epub 2010 Jan 21.
The aim of this study was to investigate whether monitoring neuromuscular block at the masseter muscle (MM) would allow faster tracheal intubation when compared with that at the adductor pollicis muscle (APM).
Twenty female patients undergoing gynecological surgery were enrolled into this study. Immediately after inducing anesthesia with fentanyl and propofol, both the left masseter and ulnar nerves were stimulated in a 2 Hz train-of-four (TOF) mode using peripheral nerve stimulators. Contractions of the MM were felt with the anesthesiologist's left hand lifting the patient's jaw and holding an anesthesia facemask, while those of the APM were visually observed. Immediately after the contracting responses of the muscles were confirmed, all of the patients received an iv bolus of vecuronium 0.1 mg kg(-1). Onset times after vecuronium were defined as the duration until the contractions became impalpable at the MM or invisible at the APM. When the contraction of the MM could no longer be felt, the conditions for laryngoscopy and tracheal intubation were assessed.
Onset time evaluated tactually at the MM (mean +/- SD, 108.4 +/- 27.7 s) was significantly shorter than that evaluated visually at the APM (181.2 +/- 32.1 s, P < 0.0001). The intubating conditions for all patients were graded as either excellent or good.
Tactual evaluation of muscle paralysis of the MM during induction of anesthesia is clinically useful since it leads to faster tracheal intubation.
本研究旨在探讨监测咬肌(MM)神经肌肉阻滞是否比拇内收肌(APM)神经肌肉阻滞能更快地进行气管插管。
本研究纳入了 20 名接受妇科手术的女性患者。在芬太尼和丙泊酚诱导麻醉后,使用周围神经刺激器以 2 Hz 四串刺激模式刺激左侧咬肌和尺神经。麻醉师用左手抬起患者的下巴并握住麻醉面罩来感觉 MM 的收缩,同时观察 APM 的收缩。在确认肌肉收缩反应后,所有患者均立即静脉注射维库溴铵 0.1mg/kg。维库溴铵给药后的起效时间定义为 MM 触诊收缩消失或 APM 可见收缩消失的时间。当 MM 的收缩无法感觉到时,评估进行喉镜检查和气管插管的条件。
MM 触诊评估的起效时间(平均 +/- 标准差,108.4 +/- 27.7s)明显短于 APM 视觉评估的起效时间(181.2 +/- 32.1s,P < 0.0001)。所有患者的插管条件均评为优秀或良好。
麻醉诱导期间 MM 肌肉瘫痪的触诊评估具有临床意义,因为它可以更快地进行气管插管。