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通过细针穿刺细胞学检查诊断婴儿胸锁乳突肌肿瘤

Diagnosis of sternomastoid tumor of infancy by fine-needle aspiration cytology.

作者信息

Kumar Bipin, Pradhan Anju

机构信息

Department of Pathology, B. P. Koirala Institute of Health Sciences, Dharan, Nepal.

出版信息

Diagn Cytopathol. 2011 Jan;39(1):13-7. doi: 10.1002/dc.21316.

Abstract

Sternomastoid tumor of infancy, also known as fibromatosis colli or muscular torticollis, is a benign fibroblastic lesion of the sternocleidomastoid muscle presenting as a firm, fusiform, non-tender neck mass of 1-3 cm in greatest dimension in the perinatal period. Various modalities are used for the diagnosis including radiographic studies, fine-needle aspiration cytology (FNAC), and open biopsy. We report eight cases of sternomastoid tumor of infancy diagnosed by FNAC. The objective of the study is to present the role of FNAC in the diagnosis of sternomastoid tumor with its cytomorphological features. FNA was done by using 23-guage needle and 10 ml disposable plastic syringe. The wet smears were fixed in 95% ethanol and processed for Papanicolaou stain. The dried smears were stained with May-Grünwald-Giemsa stain. The smears were studied for cytomorphologic features. The age of the patients ranged between 2 and 10 weeks. Male: Female ratio was 1.6:1. Six of eight had history of prolonged labor, two had history of breech presentation, and three had history of forceps assisted vaginal delivery. Cytologic findings included singly scattered and loose clusters of benign fibroblasts with moderate amount of unipolar to bipolar cytoplasm and plumped, ovoid nuclei. Many multinucleated giant cells consistent with atrophic muscle fibers were also seen. FNAC is a reliable, safe, and cost-effective method and can provide a rapid and reliable diagnosis of sternomastoid tumor of infancy.

摘要

婴儿期胸锁乳突肌肿瘤,也称为颈部纤维瘤病或肌性斜颈,是胸锁乳突肌的一种良性成纤维细胞病变,在围产期表现为最大直径为1 - 3厘米的坚实、梭形、无压痛的颈部肿块。诊断采用多种方式,包括影像学检查、细针穿刺抽吸细胞学检查(FNAC)和开放活检。我们报告8例经FNAC诊断的婴儿期胸锁乳突肌肿瘤。本研究的目的是阐述FNAC在婴儿期胸锁乳突肌肿瘤诊断中的作用及其细胞形态学特征。FNA采用23号针头和10毫升一次性塑料注射器进行。湿涂片固定于95%乙醇中,进行巴氏染色处理。干燥涂片用May-Grünwald-Giemsa染色。对涂片进行细胞形态学特征研究。患者年龄在2至10周之间。男女比例为1.6:1。8例中有6例有产程延长史,2例有臀位分娩史,3例有产钳助产阴道分娩史。细胞学检查结果包括单个散在及松散聚集的良性成纤维细胞,胞质中等量,从单极到双极,细胞核饱满、呈卵圆形。还可见许多与萎缩肌纤维一致的多核巨细胞。FNAC是一种可靠、安全且经济有效的方法,能够对婴儿期胸锁乳突肌肿瘤做出快速可靠的诊断。

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