Sharma Sonal, Mishra Kiran, Khanna Geetika
Department of Pathology, University College of Medical Sciences, Guru Teg Bahadur Hospital, Delhi, India.
Acta Cytol. 2003 May-Jun;47(3):359-62. doi: 10.1159/000326533.
To review eight cases of fibromatosis colli and assess their cytomorphologic features.
Cytologic smears from eight patients diagnosed as having fibromatosis colli on fine needle aspiration cytology were reviewed.
Cytologic features of fibromatosis colli are bland-appearing fibroblasts and degenerative atrophic skeletal muscle in a clean background. Besides these, we found a large number of muscle giant cells; numerous bland, bare nuclei; and parallel clusters of fibroblasts. Collagen was seen in all cases.
A confirmatory, noninvasive diagnosis of fibromatosis colli can be made by fine needle aspiration cytology alone; invasive diagnostic and therapeutic measures are best avoided. Excision biopsy may not be necessary and should be reserved for cases with a strong clinicopathologic suspicion of malignancy.
回顾8例颈部纤维瘤病病例并评估其细胞形态学特征。
对8例经细针穿刺细胞学诊断为颈部纤维瘤病患者的细胞学涂片进行回顾。
颈部纤维瘤病的细胞学特征为背景干净,有成纤维细胞及退行性萎缩骨骼肌,细胞表现温和。除此之外,我们发现大量肌巨细胞、众多温和的裸核以及成纤维细胞平行排列的细胞团。所有病例均可见胶原。
仅通过细针穿刺细胞学检查即可对颈部纤维瘤病做出确诊性的非侵入性诊断;最好避免采用侵入性诊断和治疗措施。切除活检可能并非必要,应仅用于临床病理高度怀疑为恶性肿瘤的病例。