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[在早期布劳洛克-陶西格吻合术后法洛四联症的根治术]

[Radical correction of Fallot's tetralogy following an earlier Blalock-Taussig anastomosis].

作者信息

Podzolkov V P, Plotnikova L R, Alimbaev S A

出版信息

Grud Serdechnososudistaia Khir. 1991 Jan(1):25-9.

PMID:2009193
Abstract

Seventy-nine radical interventions for Fallot's tetralogy after a previously established Blalock-Taussig anastomosis were conducted at Bakulev Institute of Cardiovascular Surgery, AMS USSR, from 1983 to Dec. 1989. The average age at which the radical operation was undertaken was 10.1 +/- 0.4 years. The interval between the two operations ranged from 1 year to 12 years (7.0 +/- 0.2 year on average). Thrombosis of the anastomosis occurred in 2 (2.5%) patients. Development of pulmonary hypertension was not encountered. Complications like "functional atresia" of the right-ventricular outflow tract (5.1%) and acquired atresia of the valve of the pulmonary trunk (2.5%) were encountered when the interval between the two operations was more than 7 years, and developed mostly in patients with the anastomosis formed before the age of 2 years. In 70 (88.6%) patients the subclavian artery was ligated, in 6 the opening of the anastomosis was sutured through the lumen of the respective pulmonary trunk. Surgically significant constrictions of the branches of the pulmonary arteries were revealed in 10 (12.6%) patients, which called for plastic distension during radical correction. In 7 (8.8%) patients the operative interventions were limited to infundibulectomy. Transannular plastics was necessary in more than half of the patients (55.7%). A conduit containing a xenovalve was implanted between the right ventricle and the pulmonary trunk in one (1.3%) patients. Hospital mortality was 6.3% (5 patients died). With a proper surgical approach, complications of the Blalock-Taussig anastomosis produce no essential effect on the results of radical correction, which may be carried out with a mild degree of risk and a low mortality rate.

摘要

1983年至1989年12月期间,苏联医学科学院巴库列夫心血管外科研究所对79例曾行布-塔吻合术的法洛四联症患者进行了根治性手术。进行根治性手术的平均年龄为10.1±0.4岁。两次手术的间隔时间为1年至12年(平均7.0±0.2年)。2例(2.5%)患者出现吻合口血栓形成。未发现肺动脉高压的进展。当两次手术间隔超过7年时,出现右心室流出道“功能性闭锁”(5.1%)和肺动脉干瓣膜获得性闭锁(2.5%)等并发症,且大多发生在2岁前形成吻合口的患者中。70例(88.6%)患者结扎了锁骨下动脉,6例通过相应肺动脉干腔缝合吻合口开口。10例(12.6%)患者发现肺动脉分支存在具有外科意义的狭窄,在根治性矫正时需要进行整形扩张。7例(8.8%)患者的手术干预仅限于漏斗部切除术。超过一半的患者(55.7%)需要进行跨环整形。1例(1.3%)患者在右心室和肺动脉干之间植入了含异种瓣膜的管道。医院死亡率为6.3%(5例患者死亡)。采用适当的手术方法,布-塔吻合术的并发症对根治性矫正结果无实质性影响,根治性矫正手术可在轻度风险和低死亡率下进行。

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