Pediatric Sleep Center, Tel Aviv University Faculty of Medicine, Dana Children's Hospital, Tel Aviv Souraski Medical Center, Israel.
Sleep Med. 2010 Feb;11(2):197-200. doi: 10.1016/j.sleep.2009.04.011. Epub 2010 Jan 25.
Eustachian tube dysfunction and sleep-disordered breathing (SDB) share common pathophysiologic mechanisms. Our objective was to investigate whether children referred for isolated TTI (tympanostomy tube insertion) are at increased risk for snoring and upper airway procedures.
Telephone interviews to parents of children who underwent isolated TTI and to age- and gender-matched controls were conducted.
Four hundred fifty-seven children were included in the study; 352 had isolated TTI (study group) and 105 children were controls. Twenty-two percent of children in the study group were reported to snore compared with 7.6% in the controls (p=0.001). Eighteen percent of children in the study group were reported to have undergone adenotonsillectomy compared with 4.8% in the controls (p=0.0005). Future SDB, i.e., either snoring or adenotonsillectomy following TTI, was found in 34% of children in the study group compared with 11% in the controls (p=0.0004). Children who underwent isolated TTI were at increased risk for future snoring (OR=3.4, CI: 1.6-7.2) and future adenotonsillectomy (OR=4.4, CI: 1.7-11.2).
Children who undergo isolated TTI are at increased risk for snoring and for adenotonsillectomy. We suggest that these children be followed for symptoms of SDB on a scheduled basis to allow for early diagnosis and intervention.
咽鼓管功能障碍和睡眠呼吸紊乱（SDB）具有共同的病理生理机制。我们的目的是研究因单纯性 TTI（鼓膜切开术置管）而就诊的儿童是否存在鼾症和上呼吸道手术风险增加的情况。
对接受单纯性 TTI 的儿童及其年龄和性别匹配的对照组的父母进行电话访谈。
研究共纳入 457 例儿童，其中 352 例患有单纯性 TTI（研究组），105 例为对照组。研究组有 22%的儿童报告打鼾，而对照组为 7.6%（p=0.001）。研究组有 18%的儿童报告接受了腺样体扁桃体切除术，而对照组为 4.8%（p=0.0005）。研究组有 34%的儿童在 TTI 后出现未来 SDB，即打鼾或腺样体扁桃体切除术，而对照组为 11%（p=0.0004）。与对照组相比，接受单纯性 TTI 的儿童未来发生打鼾（OR=3.4，CI：1.6-7.2）和未来接受腺样体扁桃体切除术（OR=4.4，CI：1.7-11.2）的风险增加。
接受单纯性 TTI 的儿童存在鼾症和腺样体扁桃体切除术风险增加的情况。我们建议对这些儿童进行 SDB 症状的定期随访，以便早期诊断和干预。
