Bawa Bhupinder, Bai Jianfa, Whitehair Mike, Purvis Tanya, Debey Brad M
Department of Diagnostic Medicine/Pathobiology, College of Veterinary Medicine, Kansas State University, 1800 Denison Avenue, Manhattan, KS 66506, USA.
J Vet Diagn Invest. 2010 Jan;22(1):108-11. doi: 10.1177/104063871002200122.
Nocardia spp. are recognized as a cause of bovine mastitis, cutaneous or subcutaneous abscesses, pneumonia, and disseminated disease. Abortion caused by Nocardia spp. is uncommon, and only a few sporadic cases have been reported in horses, pigs, and cattle. In all previous reports, of nocardial abortion, the causative agent was identified as Nocardia asteroides. The current report describes an aborted bovine fetus that was infected with Nocardia farcinica. Placenta, abomasal fluid, lung, liver, and kidney specimens from a late-term bovine abortion were submitted to the Kansas State Veterinary Diagnostic Laboratory. The gross findings included purulent exudate in the placenta and numerous abscesses in lung. Histologically, there was necrotizing and suppurative placentitis, pyogranulomatous pneumonia, and nephritis with numerous intralesional branching and filamentous, Gram-positive bacteria. Nocardia farcinica was isolated by bacteriology, and the bacteriology result was confirmed by 2 established polymerase chain reaction protocols and by DNA sequencing.
诺卡氏菌被认为是牛乳腺炎、皮肤或皮下脓肿、肺炎及播散性疾病的病因。诺卡氏菌引起的流产并不常见，仅在马、猪和牛中有少数散发病例报道。在之前所有关于诺卡氏菌性流产的报告中，病原体均被鉴定为星形诺卡氏菌。本报告描述了一头流产的牛胎儿感染了豚鼠耳炎诺卡氏菌。来自一头晚期流产母牛的胎盘、皱胃液、肺、肝和肾标本被提交至堪萨斯州兽医诊断实验室。大体检查结果包括胎盘脓性渗出物及肺内大量脓肿。组织学检查显示有坏死性和化脓性胎盘炎、脓性肉芽肿性肺炎以及肾炎，病灶内可见大量分支状和丝状革兰氏阳性菌。通过细菌学方法分离出豚鼠耳炎诺卡氏菌，细菌学结果经两种既定的聚合酶链反应方案及DNA测序得以证实。
