Department of Pathology, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran.
Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran.
Vet Med Sci. 2024 May;10(3):e1433. doi: 10.1002/vms3.1433. Epub 2024 Mar 23.
A 3-year-old Holstein cow was examined in an intensive system due to unilateral swelling in the mandible. A right mandibular mass was associated with painful mastication and Ptyalism. In palpation, the mass was raised, ulcerated, attached to the mandible bone and firm, approximately 17 × 12 × 10 cm in size. The lesion was sampled, and after routine bacteriology and histopathology procedures, the occurrence of lumpy jaw caused by Nocardia farcinica was confirmed. The bacterium was analysed using genome sequencing and new strain called Najm 114. Due to the risk of zoonosis of the isolated agent, the cow was euthanized. This is the first report of lumpy jaw caused by N. farcinica in a cow. This study showed that N. farcinica should be considered a possible etiological agent for lumpy jaw in cattle.
一头三岁的荷斯坦奶牛因下颌单侧肿胀而在强化系统中接受检查。右侧下颌肿块与咀嚼疼痛和流涎有关。触诊时，肿块隆起、溃疡、附着于下颌骨且坚硬，大小约为 17×12×10 厘米。对病变进行了取样，经过常规细菌学和组织病理学程序，证实了由诺卡氏菌引起的块状颚。该细菌使用基因组测序进行了分析，并命名为 Najm 114。由于分离剂的人畜共患病风险，奶牛被安乐死。这是首次报道牛的诺卡氏菌引起的块状颚。本研究表明，诺卡氏菌应被视为牛块状颚的一种可能病因。
