From the Departments of Obstetrics and Gynecology, University of Tennessee Medical Center, Knoxville, Tennessee; and Washington University in Saint Louis, Saint Louis, Missouri.
Obstet Gynecol. 2010 Feb;115(2 Pt 2):417-419. doi: 10.1097/AOG.0b013e3181bd1a8b.
In patients with medically refractory seizures, vagal nerve stimulation is becoming an increasingly common adjunctive therapy. Although its safety and efficacy have been proven in the general population, little is known about its use during pregnancy.
A 19-year-old primigravid woman presented during the first trimester for routine prenatal care. She had a past medical history significant for generalized tonic-clonic seizure disorder since childhood. Multiple medical regimens had failed, and a vagal nerve stimulator was implanted approximately 2 months before conception. The patient continued to take phenytoin, with improved seizure control. She had a term spontaneous delivery complicated by mild preeclampsia.
Adjunctive treatment of medically refractory seizures with a vagal nerve stimulator is a viable option during pregnancy.
在药物难治性癫痫患者中，迷走神经刺激术正成为一种越来越常见的辅助治疗手段。尽管其在一般人群中的安全性和有效性已得到证实，但关于其在怀孕期间的使用知之甚少。
一名 19 岁的初产妇在孕早期接受常规产前检查。她自幼患有全身性强直阵挛性癫痫。多种药物治疗方案均失败，大约在受孕前 2 个月植入了迷走神经刺激器。患者继续服用苯妥英钠，癫痫发作得到了改善。她足月自然分娩，但并发轻度子痫前期。
在怀孕期间，使用迷走神经刺激器辅助治疗药物难治性癫痫是一种可行的选择。
