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脑和神经细胞膜的物理化学:概述。

The physical chemistry of brain and neural cell membranes: an overview.

出版信息

Neurochem Res. 2010 May;35(5):681-7. doi: 10.1007/s11064-010-0121-7. Epub 2010 Jan 22.

DOI:10.1007/s11064-010-0121-7
PMID:20094775
Abstract

The formation of cell membranes through the physical-chemical interaction of two hydrophilic colloidal fluids is applied to the formation of the membranes of brain and neural cells. Also described is the membrane mechanism of transfer of ions and compounds necessary for brain and neural cell functions into the cerebrospinal fluid through the blood-brain barrier. Changes in the cerebrospinal fluid giving rise to degradation of brain and neural cells and the formation of precipitates within the brain are considered. Monitoring of electrolyte changes in metabolic fluids is shown to be a possible method of predicting the onset of degenerate brain conditions.

摘要

细胞膜通过两种亲水胶体的物理化学相互作用形成,该原理被应用于脑和神经细胞的细胞膜形成。本文还描述了离子和化合物通过血脑屏障从血液向脑脊液转移的膜机制,这些离子和化合物是脑和神经细胞功能所必需的。文中考虑了导致脑和神经细胞退化以及在脑内形成沉淀物的脑脊液变化。代谢液中电解质变化的监测被认为是预测退行性脑状况发生的一种可能方法。

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J Chin Med Assoc. 2009 Jul;72(7):368-73. doi: 10.1016/S1726-4901(09)70389-2.
2
Continuous CSF drainage in AD: results of a double-blind, randomized, placebo-controlled study.阿尔茨海默病中脑脊液持续引流:一项双盲、随机、安慰剂对照研究的结果
Neurology. 2008 Jul 15;71(3):202-9. doi: 10.1212/01.wnl.0000316197.04157.6f. Epub 2008 Jun 4.
3
Anat Res Int. 2013;2013:596027. doi: 10.1155/2013/596027. Epub 2013 Dec 12.
4
A case of difficult management of fluid-electrolyte imbalance in choroid plexus papilloma.脉络丛乳头状瘤患者水电解质失衡的难治病例
Neurol Med Chir (Tokyo). 2014;54(8):659-63. doi: 10.2176/nmc.cr2012-0380. Epub 2013 Nov 20.
5
Catastrophic electrolyte imbalance caused by excessive production and overdrainage of cerebrospinal fluid in an infant with choroid plexus papilloma.
Childs Nerv Syst. 2011 Jul;27(7):1153-6. doi: 10.1007/s00381-011-1459-0. Epub 2011 Apr 19.
Cleavage and conformational changes of tau protein follow phosphorylation during Alzheimer's disease.
在阿尔茨海默病中,tau蛋白的切割和构象变化发生在磷酸化之后。
Int J Exp Pathol. 2008 Apr;89(2):81-90. doi: 10.1111/j.1365-2613.2007.00568.x.
4
The olfactory route for cerebrospinal fluid drainage into the peripheral lymphatic system.脑脊液引流至外周淋巴系统的嗅觉途径。
Neuropathol Appl Neurobiol. 2006 Aug;32(4):388-96. doi: 10.1111/j.1365-2990.2006.00737.x.
5
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Crit Care Resusc. 2002 Dec;4(4):301-6.
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