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日本泌尿外科的最小切口内镜手术(MIES):肾上腺切除术、根治性肾切除术和根治性前列腺切除术的结果

Minimum incision endoscopic surgery (MIES) in Japanese urology: results of adrenalectomy, radical nephrectomy and radical prostatectomy.

作者信息

Kihara K, Kobayashi T, Kawakami S, Fujii Y, Kageyama Y, Masuda H

机构信息

Department of Urology, Tokyo Medical and Dental University, Graduate School, Tokyo, Japan.

出版信息

Aktuelle Urol. 2010 Jan;41 Suppl 1:S15-9. doi: 10.1055/s-0029-1224662. Epub 2010 Jan 21.

DOI:10.1055/s-0029-1224662
PMID:20094945
Abstract

AIM

The aim of this study was to evaluate the feasibility of our minimum incision endoscopic surgeries (MIES), adrenalectomy, radical nephrectomy and radical prostatectomy, which are operated via a single minimum incision which narrowly permits extraction of the specimen, using an endoscope, without gas insufflation, without any trocar ports and without injury to the peritoneum. These operations have been developed in our department in the late 1990 s and have since been performed in more than 1000 patients and certified as advanced surgery by the Japanese government in 2006.

METHODS

Adrenalectomy, radical nephrectomy and radical prostatectomy were carried out via a single minimum incision under the conditions of gasless, portless (without trocar ports), intact peritoneum and at low cost with reusable devices. The anatomic plane was separated through the incision and a wide working space was made extraperitoneally. New devices were made especially for this operation in our department, which are now commercially available. The results of the most recent consecutive cases (2005-2007) are evaluated. The results of adrenalectomy and radical nephrectomy performed by 12 operators including inexperienced doctors were compared with the initial results performed by 2 operators, mostly by one operator.

RESULTS

In the recent 60 cases of adrenalectomy, the average length of incision, operative time, estimated blood loss were 5.7 cm (5.6 cm in the initial 30 cases), 156 min (147 min) and 174 ml (139 ml), respectively. A complication was observed in one case, injury to the renal artery. Blood transfusion was not performed. Average days to oral feeding, to long walking (more than 100 m) and to possible minimal hospital stay were 1.3 days (2 days), 1.1 days (1.1 days) and 1.9 days (4.6 days), respectively. In the recent 80 cases of radical nephrectomy, the average length of incision, operative time, estimated blood loss were 6.6 cm (6.6 cm in the initial 80 cases), 192 min (186 min) and 315 ml (324 ml), respectively. Complications were not observed in any of the cases (2) and blood transfusion was performed in 1 case (3). Average days to oral feeding, to long walking (more than 100 m) and to possible minimal hospital stay were 1.1 days (1.4 days), 1.2 days (1.4 days) and 1.9 days (4.8 days), respectively. In the recent 50 cases of radical prostatectomy, the average length of incision and operative time were 5.9 cm and 261 min, respectively. Two complications (small rectal injuries) were observed and one blood transfusion was performed. Average days to oral feeding, to long walking (more than 100 m) and possible minimal hospital stay were 1.0 days, 1.0 days and 2.4 days, respectively. Wound pain was minimal and analgesics were generally not required on the second postoperative day in the above 3 operations. Although prophylactic antibiotics were not used in the recent cases of adrenalectomy and radical nephrectomy, surgical site infection was not observed.

CONCLUSION

Minimum incision endoscopic surgery (MIES) in Japanese urology is a safe, reproducible, cost-effective and minimally invasive treatment option for adrenal tumor, renal cell carcinoma and prostate carcinoma.

摘要

目的

本研究旨在评估我院最小切口内镜手术(MIES)、肾上腺切除术、根治性肾切除术和根治性前列腺切除术的可行性。这些手术通过单一最小切口进行,该切口仅允许使用内窥镜在不进行气体充气、不使用任何套管针端口且不损伤腹膜的情况下取出标本。这些手术于20世纪90年代后期在我院开展,自那时起已在1000多名患者中实施,并于2006年被日本政府认证为先进手术。

方法

在无气、无端口(不使用套管针端口)、腹膜完整且使用可重复使用设备成本较低的条件下,通过单一最小切口进行肾上腺切除术、根治性肾切除术和根治性前列腺切除术。通过切口分离解剖平面,并在腹膜外形成广阔的操作空间。我院专门为此手术制作了新设备,目前已投入商业使用。对最近连续病例(2005 - 2007年)的结果进行评估。将包括经验不足医生在内的12名操作者进行的肾上腺切除术和根治性肾切除术的结果与最初由2名操作者(主要由1名操作者)进行的结果进行比较。

结果

在最近60例肾上腺切除术中,切口平均长度、手术时间、估计失血量分别为5.7 cm(最初30例为5.6 cm)、156分钟(147分钟)和174毫升(139毫升)。观察到1例并发症,即肾动脉损伤。未进行输血。开始经口进食、长距离行走(超过100米)及可能的最短住院天数的平均值分别为1.3天(2天)、1.1天(1.1天)和1.9天(4.6天)。在最近80例根治性肾切除术中,切口平均长度、手术时间、估计失血量分别为6.6 cm(最初80例为6.6 cm)、192分钟(186分钟)和315毫升(324毫升)。所有病例(2例)均未观察到并发症,1例(3%)进行了输血。开始经口进食、长距离行走(超过100米)及可能的最短住院天数的平均值分别为1.1天(1.4天)、1.2天(1.4天)和1.9天(4.8天)。在最近50例根治性前列腺切除术中,切口平均长度和手术时间分别为5.9 cm和261分钟。观察到2例并发症(直肠小损伤),进行了1次输血。开始经口进食、长距离行走(超过100米)及可能的最短住院天数的平均值分别为1.0天、1.0天和2.4天。在上述3种手术中,伤口疼痛轻微,术后第二天一般无需使用镇痛药。尽管最近的肾上腺切除术和根治性肾切除术病例未使用预防性抗生素,但未观察到手术部位感染。

结论

日本泌尿外科的最小切口内镜手术(MIES)是治疗肾上腺肿瘤、肾细胞癌和前列腺癌的一种安全、可重复、经济有效且微创的治疗选择。

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