从轮环藤茎皮中分离得到的新强心苷。

New cardenolides from the stem bark of Trewia nudiflora.

机构信息

Natural Products Research Laboratories, Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow, UK.

出版信息

Fitoterapia. 2010 Sep;81(6):536-9. doi: 10.1016/j.fitote.2010.01.016. Epub 2010 Jan 25.

DOI:10.1016/j.fitote.2010.01.016

PMID:20097274

Abstract

Phytochemical investigation of the stem bark of Trewia nudiflora led to the isolation of two new cardenolides, trewianin (1) and trewioside (2), along with scopoletin (3) and indole-3-carboxylic acid (4). Structures were established by 1D- and 2D NMR spectroscopy, HR-MS analysis, and by comparison with literature data.

摘要

从 Trewia nudiflora 的茎皮中进行植物化学研究，分离得到了两个新的卡烯内酯，trewianin（1）和 trewioside（2），以及东莨菪素（3）和吲哚-3-羧酸（4）。通过 1D 和 2D NMR 光谱、高分辨率质谱分析以及与文献数据的比较，确定了它们的结构。