Trabelsi Y, Tabka Z, Richalet J-P, Bouchez-Buvry A
Laboratoire de physiologie et des explorations fonctionnelles, faculté de médecine, université de Sousse, 4002 Sousse, Tunisie.
Arch Pediatr. 2010 Mar;17(3):243-8. doi: 10.1016/j.arcped.2009.11.025. Epub 2010 Jan 25.
The purpose of this study was to set lung function prediction equations in Tunisian children with standing height and pubertal stage as the independent variables.
Spirometric values were measured with a Minato portable Spirometer in 684 asymptomatic Tunisian children (351 boys and 333 girls), 8 to 16 years of age. The specific parameters of pulmonary function that were measured included Forced Vital Capacity (FVC), Forced Expiratory Volume in 1 second (FEV(1)), Peak Expiratory Flow (PEF), Maximal Expiratory Flow at 50% of the vital capacity (MEF(50)), and Maximum Mild Expiratory Flow between 25 and 75% (MMEF(25-75)). The pubertal status was assessed for males and females according to the Tanner method.
A large variation was observed in the distribution of children's age and height by pubertal stages in both sexes. Multiple regression equations for FVC, FEV(1), MEF(50), MEF(25-75), and PEF for both sexes are presented with standing height and pubertal stage as the independent variables.
The establishment of validated reference values relevant to the ethnic group of the local population should significantly improve medical surveillance of respiratory diseases in Tunisian children.
本研究旨在以身高和青春期阶段作为自变量，建立突尼斯儿童的肺功能预测方程。
使用美能达便携式肺活量计对684名8至16岁无症状突尼斯儿童（351名男孩和333名女孩）进行肺量计测量。所测量的肺功能具体参数包括用力肺活量（FVC）、第1秒用力呼气量（FEV(1)）、呼气峰值流速（PEF）、肺活量50%时的最大呼气流量（MEF(50)）以及25%至75%之间的最大呼气中期流速（MMEF(25 - 75)）。根据坦纳方法评估男性和女性的青春期状态。
在两个性别的青春期阶段，观察到儿童年龄和身高分布存在很大差异。给出了以身高和青春期阶段作为自变量的两性FVC、FEV(1)、MEF(50)、MEF(25 - 75)和PEF的多元回归方程。
建立与当地人群种族相关的有效参考值应能显著改善突尼斯儿童呼吸道疾病的医学监测。
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