Department of Radiology and Research Institute of Radiological Science, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.
J Magn Reson Imaging. 2010 Feb;31(2):365-72. doi: 10.1002/jmri.22057.
To compare two different injection rates for gadoxetic acid-enhanced hepatic arterial phase images on hepatic dynamic MRI.
Hepatic arterial phase images were obtained after an intravenous bolus injection of gadoxetic acid at a rate of 1 mL/second in 62 patients and 2 mL/second in 64 patients on a 3 Tesla MR scanner using a test-bolus injection method. The signal-to-noise ratios (SNR) of the liver, portal vein, hepatic vein, aorta, spleen and pancreas were measured. The contrast-to-noise ratio (CNR) of hypervascular hepatic tumors was calculated. Two radiologists independently scored items to evaluate image quality of hepatic arterial phase and detected hypervascular hepatocellular carcinoma (HCC).
The SNR of the aorta on the arterial phase images was significantly higher in the 1 mL/second group (235.43 +/- 82.59) than in the 2 mL/second group (190.94 +/- 96.90, P < 0.05). The SNRs of the liver, spleen and pancreas, the CNRs of hypervascular hepatic tumors, the detection rate of hypervascular HCC and subjective ratings for the optimal arterial enhancement were comparable between the two groups.
Injection rates of 2 mL/second and 1 mL/second provided comparable image qualities on arterial phase images of hepatic dynamic MRI using gadoxetic acid.
比较两种不同的钆塞酸增强肝动脉期磁共振成像的注射速率。
采用测试团注法，在 3.0T 磁共振扫描仪上对 62 例患者以 1ml/秒的速率和 64 例患者以 2ml/秒的速率静脉团注钆塞酸后获得肝动脉期图像。测量肝、门静脉、肝静脉、主动脉、脾和胰腺的信噪比（SNR）。计算富血管性肝肿瘤的对比噪声比（CNR）。两名放射科医生独立对肝动脉期图像质量和富血管性肝细胞癌（HCC）的检出进行评分。
1ml/秒组动脉期主动脉 SNR（235.43±82.59）明显高于 2ml/秒组（190.94±96.90，P＜0.05）。两组肝、脾、胰腺 SNR、富血管性肝肿瘤 CNR、富血管性 HCC 检出率和最佳动脉强化主观评分相当。
在使用钆塞酸的肝动态磁共振成像中，2ml/秒和 1ml/秒的注射速率均可提供相似的动脉期图像质量。
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