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用于磁共振成像(MRI)增强造影的肝脏特异性造影剂:在肿瘤成像中的作用

Liver-specific agents for contrast-enhanced MRI: role in oncological imaging.

作者信息

Thian Yee Liang, Riddell Angela M, Koh Dow-Mu

机构信息

Department of Diagnostic Imaging, National University Hospital Singapore, 5 Lower Kent Ridge Road, Singapore 119074.

Department of Diagnostic Radiology, Royal Marsden Hospital Foundation Trust, Downs Road, Sutton, Surrey SM2 5PT, UK.

出版信息

Cancer Imaging. 2013 Dec 30;13(4):567-79. doi: 10.1102/1470-7330.2013.0050.

Abstract

Liver-specific magnetic resonance (MR) contrast agents are increasingly used in evaluation of the liver. They are effective in detection and morphological characterization of lesions, and can be useful for evaluation of biliary tree anatomy and liver function. The typical appearances and imaging pitfalls of various tumours at MR imaging performed with these agents can be understood by the interplay of pharmacokinetics of these contrast agents and transporter expression of the tumour. This review focuses on the applications of these agents in oncological imaging.

摘要

肝脏特异性磁共振(MR)造影剂在肝脏评估中的应用越来越广泛。它们在病变的检测和形态学特征描述方面很有效,并且可用于评估胆管树解剖结构和肝功能。通过这些造影剂的药代动力学与肿瘤转运体表达之间的相互作用,可以理解使用这些造影剂进行MR成像时各种肿瘤的典型表现及成像陷阱。本综述重点关注这些造影剂在肿瘤成像中的应用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/33ab/3893895/2367f9534631/ci13005001.jpg

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