Okamoto Norihiro, Maeda Koutarou, Hanai Tsunekazu, Sato Harunobu, Masumori Kouji, Katsuno Hidetoshi, Maruta Morito
Department of Surgery, Fujita Health University School of Medicine, Toyoake, Japan.
Int Surg. 2009 Jan-Feb;94(1):54-7.
Metachronous multiple carcinomas at the site of a stoma is a rare condition after surgery. A 67-year-old man with a second tumor at the stoma site 15 years after abdominoperineal resection for rectal carcinoma is reported herein with a review of the Japanese literature. The patient visited our hospital 20 years after initial surgery, presenting with constipation and increasing tumor size in the stoma. A biopsy specimen of the tumor revealed adenocarcinoma. Block resection of the sigmoid colon and colostomy with the adjacent abdominal wall was performed. Histopathological examination showed a well-differentiated adenocarcinoma in the stoma invading the adjacent skin. A median of 144 months from the initial operation was documented in 23 cases reported.
造口部位异时性多发癌是手术后罕见的情况。本文报道了一名67岁男性，在因直肠癌行腹会阴切除术后15年，造口部位出现了第二处肿瘤，并对日本文献进行了回顾。该患者在初次手术后20年就诊于我院，表现为便秘及造口处肿瘤增大。肿瘤活检标本显示为腺癌。遂行乙状结肠整块切除及与相邻腹壁的结肠造口术。组织病理学检查显示造口处为高分化腺癌，侵犯相邻皮肤。在报道的23例病例中，距初次手术的中位时间为144个月。
